Improved mucoadhesion, permeation and in vitro anticancer potential of synthesized thiolated acacia and karaya gum combination: A systematic study
N Munot, U Kandekar, C Rikame, A Patil, P Sengupta… - Molecules, 2022 - mdpi.com
Thiolation of polymers is one of the most appropriate approaches to impart higher
mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia …
mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia …
Lipid complex-itraconazole in thermosensitive mucoadhesive vaginal gel to enhance the effectiveness of therapy for vulvovaginal candidiasis: Formulation …
Purpose This study aimed to produce lipid complex-ITR (CL-ITR) to enhance the solubility of
ITR which is then made into an in situ vaginal gel to maximize the local therapeutic effect of …
ITR which is then made into an in situ vaginal gel to maximize the local therapeutic effect of …
Development and evaluation of combined effect buccal films for treatment of oral candidiasis
D Arslan, Ö Akbal Dağıstan, O Sagirli… - AAPS …, 2022 - Springer
Buccal film formulations, including antifungal nystatin, anti-inflammatory agent
hydrocortisone acetate, and local anesthetic lidocaine hydrochloride for pain relief, were …
hydrocortisone acetate, and local anesthetic lidocaine hydrochloride for pain relief, were …
Evaluation of Usnea barbata (L.) Weber ex FH Wigg Extract in Canola Oil Loaded in Bioadhesive Oral Films for Potential Applications in Oral Cavity Infections and …
Usnea lichens are known for their beneficial pharmacological effects with potential
applications in oral medicine. This study aims to investigate the extract of Usnea barbata (L.) …
applications in oral medicine. This study aims to investigate the extract of Usnea barbata (L.) …
Mucoadhesive buccal tablet of leuprolide and its fatty acid conjugate: Design, in vitro evaluation and formulation strategies
This study aimed to design mucoadhesive buccal tablets of leuprolide (LEU) and to
manufacture and evaluate the properties of buccal tablets containing LEU-oleic acid …
manufacture and evaluate the properties of buccal tablets containing LEU-oleic acid …
Preparation and In Vitro Evaluation of Levofloxacin-Loaded Floating Tables Using Various Rate-Controlling Agents
Floating tablets are a new approach to extending the time a drug is in the stomach to
improve therapy outcomes. Floating tablets were formulated with the drug, the polymers …
improve therapy outcomes. Floating tablets were formulated with the drug, the polymers …
Optimization of a Mucoadhesive Vaginal Gel Containing Clotrimazole Using a D-Optimal Experimental Design and Multivariate Analysis
The aim of this study was to develop a suitable clotrimazole (CLT)-loaded mucoadhesive
vaginal gel (CLT-MVG) for topical applications in vaginal candidiasis. Ten CLT-MVG …
vaginal gel (CLT-MVG) for topical applications in vaginal candidiasis. Ten CLT-MVG …
The free hydralazine anti-hypertensive drug and new salts with improved solubility
PP Firmino, HO Pedro, CCP da Silva… - Journal of Molecular …, 2023 - Elsevier
Although long used as an antihypertensive drug because of its vasodilator properties,
Hydralazine (HDZ) has received renewed attention in the last few years due to its secondary …
Hydralazine (HDZ) has received renewed attention in the last few years due to its secondary …
Approaches to Improve Oral Bioavailability of Antihypertensive Drugs: A Mini-Review
R Dole, D Kothapally, S Chukkala… - Journal of Drug Delivery …, 2023 - jddtonline.info
Hypertension elevates the risk of heart disease and stroke which are one of the most
frequent causes of death. Fortunately, hypertension is manageable with the use of anti …
frequent causes of death. Fortunately, hypertension is manageable with the use of anti …