Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

As a chemical transmitter in the mammalian central nervous system, nitric oxide (NO) is still
thought a bit of an oddity, yet this role extends back to the beginnings of the evolution of the …

Clarity about the nitric oxide (NO) concentrations existing physiologically is essential for
developing a quantitative understanding of NO signalling, for performing experiments with …

The effects of nitric oxide in biological systems depend on its steady-state concentration and
where it is being produced. The organ where nitric oxide is produced is relevant, and within …

Electronic cigarette (e-cig) vaping (ECV) has been proposed as a safer alternative to
tobacco cigarette smoking (TCS); however, this remains controversial due to a lack of long …

Calcific aortic valve disease (CAVD) is an increasingly prevalent condition, and endothelial
dysfunction is implicated in its etiology. We previously identified nitric oxide (NO) as a …

The identity of the specific nitric oxide dioxygenase (NOD) that serves as the main in vivo
regulator of O2-dependent NO degradation in smooth muscle remains elusive. Cytoglobin …

Abstract Toll-like receptors (TLRs), well-characterized pattern-recognizing receptors of the
innate arm of the immune system, are vital in detecting pathogen-associated molecular …

Over time, the proportion of resistant bacteria will increase. This is a major concern.
Therefore, effective and biocompatible therapeutic strategies against these bacteria are …

Abstract Paracrine superoxide (O 2•−) and hydrogen peroxide (H 2 O 2) signaling critically
depends on these substances' concentrations, half-lives and transport ranges in …