Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders
The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-
onset dementia. The diagnosis of bvFTD remains challenging because of the limited …
onset dementia. The diagnosis of bvFTD remains challenging because of the limited …
The multifaceted role of neurofilament light chain protein in non-primary neurological diseases
The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
Cerebrospinal fluid biomarkers in patients with unipolar depression compared with healthy control individuals: a systematic review and meta-analysis
IV Mousten, NV Sørensen, RHB Christensen… - JAMA …, 2022 - jamanetwork.com
Importance Depression has been associated with alterations in neurotransmitters,
hormones, and inflammatory and neurodegenerative biomarkers, and biomarkers quantified …
hormones, and inflammatory and neurodegenerative biomarkers, and biomarkers quantified …
Neurofilament-light, a promising biomarker: analytical, metrological and clinical challenges
Neurofilament-light chain (Nf-L) is a non-specific early-stage biomarker widely studied in the
context of neurodegenerative diseases (NDD) and traumatic brain injuries (TBI), which can …
context of neurodegenerative diseases (NDD) and traumatic brain injuries (TBI), which can …
Neurofilament light chain as neuronal injury marker–what is needed to facilitate implementation in clinical laboratory practice?
B Arslan, H Zetterberg - Clinical Chemistry and Laboratory Medicine …, 2023 - degruyter.com
Neurobiomarkers have attracted significant attention over the last ten years. One promising
biomarker is the neurofilament light chain protein (NfL). Since the introduction of …
biomarker is the neurofilament light chain protein (NfL). Since the introduction of …
Advances and controversies in frontotemporal dementia: diagnosis, biomarkers, and therapeutic considerations
Frontotemporal dementia comprises a group of clinical syndromes that are characterised by
progressive changes in behaviour, executive function, or language. The term frontotemporal …
progressive changes in behaviour, executive function, or language. The term frontotemporal …
Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls
The recent introduction of new-generation immunoassay methods allows the reliable
quantification of structural brain markers in peripheral matrices. Neurofilament light chain …
quantification of structural brain markers in peripheral matrices. Neurofilament light chain …
Young‐onset dementia diagnosis, management and care: a narrative review
Young‐onset dementia comprises a heterogeneous range of dementias, with onset at less
than 65 years of age. These include primary dementias such as Alzheimer disease …
than 65 years of age. These include primary dementias such as Alzheimer disease …
Cerebrospinal fluid neurofilament light chain differentiates primary psychiatric disorders from rapidly progressive, Alzheimer's disease and frontotemporal disorders in …
Introduction Many patients with cognitive and neuropsychiatric symptoms face diagnostic
delay and misdiagnosis. We investigated whether cerebrospinal fluid (CSF) neurofilament …
delay and misdiagnosis. We investigated whether cerebrospinal fluid (CSF) neurofilament …
Biomarkers in the cerebrospinal fluid of patients with psychotic disorders compared to healthy controls: a systematic review and meta-analysis
TB Rømer, R Jeppesen, RHB Christensen… - Molecular …, 2023 - nature.com
Psychotic disorders are severe mental disorders with poorly understood etiology.
Biomarkers in the cerebrospinal fluid (CSF) could provide etiological clues and diagnostic …
Biomarkers in the cerebrospinal fluid (CSF) could provide etiological clues and diagnostic …