Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Significance of singlet oxygen molecule in pathologies

K Murotomi, A Umeno, M Shichiri, M Tanito… - International Journal of …, 2023 - mdpi.com
Reactive oxygen species, including singlet oxygen, play an important role in the onset and
progression of disease, as well as in aging. Singlet oxygen can be formed non …

Oxidative stress is the pivot for PM2. 5-induced lung injury

T Hou, L Zhu, Y Wang, L Peng - Food and Chemical Toxicology, 2024 - Elsevier
Abstract Fine particulate matter (PM2. 5) is a primary air pollutant recognized worldwide as a
serious threat to public health. PM2. 5, which has a diameter of less than 2.5 μm, is known to …

The impact of outdoor pollution and extreme temperatures on asthma‐related outcomes: A systematic review for the EAACI guidelines on environmental science for …

I Agache, C Canelo‐Aybar, I Annesi‐Maesano… - Allergy, 2024 - Wiley Online Library
Air pollution is one of the biggest environmental threats for asthma. Its impact is augmented
by climate change. To inform the recommendations of the EAACI Guidelines on the …

Mechanisms of airway epithelial injury and abnormal repair in asthma and COPD

KL Raby, C Michaeloudes, J Tonkin, KF Chung… - Frontiers in …, 2023 - frontiersin.org
The airway epithelium comprises of different cell types and acts as a physical barrier
preventing pathogens, including inhaled particles and microbes, from entering the lungs …

[HTML][HTML] Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis

C Bao, C Liu, Q Liu, L Hua, J Hu, Z Li, S Xu - International …, 2022 - Elsevier
Background and purpose Ferroptosis is closely associated with respiratory diseases;
however, the relationship between ferroptosis and neutrophilic asthma remains unknown …

Co-exposure to polystyrene microplastics and di-(2-ethylhexyl) phthalate aggravates allergic asthma through the TRPA1-p38 MAPK pathway

Q Han, X Gao, S Wang, Z Wei, Y Wang, K Xu, M Chen - Toxicology Letters, 2023 - Elsevier
Increasing attention has been paid to the potential impact of microplastics (MPs) pollution on
human health. MPs and phthalates coexist in the environment, however, the effects of …

Multi-omics profiling approach to asthma: an evolving paradigm

Y Gautam, E Johansson, TB Mersha - Journal of personalized medicine, 2022 - mdpi.com
Asthma is a complex multifactorial and heterogeneous respiratory disease. Although
genetics is a strong risk factor of asthma, external and internal exposures and their …

Reactive X (where X= O, N, S, C, Cl, Br, and I) species nanomedicine

K Wang, W Mao, X Song, M Chen, W Feng… - Chemical Society …, 2023 - pubs.rsc.org
Reactive oxygen, nitrogen, sulfur, carbonyl, chlorine, bromine, and iodine species (RXS,
where X= O, N, S, C, Cl, Br, and I) have important roles in various normal physiological …

The impact of indoor pollution on asthma‐related outcomes: a systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma

I Agache, C Canelo‐Aybar, I Annesi‐Maesano… - Allergy, 2024 - Wiley Online Library
Systematic review using GRADE of the impact of exposure to volatile organic compounds
(VOCs), cleaning agents, mould/damp, pesticides on the risk of (i) new‐onset asthma …