Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

Light exerts a range of powerful biological effects beyond image vision, including mood and
learning regulation. While the source of photic information affecting mood and cognitive …

The stereotyped features of neuronal circuits are those most likely to explain the remarkable
capacity of the brain to process information and govern behaviors, yet it has not been …

Neocortical areas communicate through extensive axonal projections, but the logic of
information transfer remains poorly understood, because the projections of individual …

It has been known for decades that degeneration of the locus coeruleus (LC), the major
noradrenergic nucleus in the brain, occurs in both Alzheimer's disease (AD) and Parkinson's …

Psilocybin is a psychedelic with therapeutic potential. While there is growing evidence that
psilocybin exerts its beneficial effects through enhancing neural plasticity, the exact brain …

In rodents, the medial aspect of the secondary motor cortex (M2) is known by other names,
including medial agranular cortex (AGm), medial precentral cortex (PrCm), and frontal …

Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the
formation of associations between sensory stimuli and an ensuing threat. However, how the …

Highlights•Individuals differ in the perception and adaptation to aversive and stressful
stimuli.•Stress-susceptibility is associated with functional changes in specific neural …