Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …

With the development of regenerative medicine, a variety of mesenchymal stem cells
(MSCs) are increasingly considered for the treatment of premature ovarian failure (POF) …

Primary ovarian insufficiency (POI) is a clinical syndrome of ovarian dysfunction
characterized by premature exhaustion of primordial follicles. POI causes infertility, severe …

The oocyte requires a vast supply of energy after fertilization to support critical events such
as spindle formation, chromatid separation, and cell division. Until blastocyst implantation …

Devastating human neuromuscular disorders have been associated to defects in the ATP
synthase. This enzyme is found in the inner mitochondrial membrane and catalyzes the last …

Background With the development of regenerative medicine and tissue engineering
technology, almost all stem cell therapy is efficacious for the treatment of premature ovarian …

Primary ovarian insufficiency (POI) is defined by the loss or dysfunction of ovarian follicles
associated with amenorrhea before the age of 40. Symptoms include hot flashes, sleep …

Ovarian infertility and subfertility presenting with premature ovarian insufficiency (POI) and
diminished ovarian reserve are major issues facing the developed world due to the trend of …

Increasingly, mitochondria are being recognized as having an important role in fertility.
Indeed in assisted reproductive technologies mitochondrial function is a key indicator of …

Oxygen deprivation affects human health by modulating system as well as cellular
physiology. Hypoxia generates reactive oxygen species (ROS), causes oxidative stress and …