[HTML][HTML] Autoimmunity to neuronal nicotinic acetylcholine receptors

M Pechlivanidou, E Ninou, K Karagiorgou… - Pharmacological …, 2023 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) are widely expressed in many and diverse cell
types, participating in various functions of cells, tissues and systems. In this review, we focus …

[HTML][HTML] Autoimmunity in psychotic disorders. Where we stand, challenges and opportunities

M Mané-Damas, C Hoffmann, S Zong, A Tan… - Autoimmunity …, 2019 - Elsevier
Psychotic disorders are debilitating mental illnesses associated with abnormalities in
various neurotransmitter systems. The development of disease-modifing therapies has been …

Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral …

E Darrau, E Jacquemet, S Pons, L Schlick… - Translational …, 2024 - nature.com
There is growing evidence that autoantibodies (AAbs) against proteins expressed in the
brain are playing an important role in neurological and psychiatric disorders. Here, we …

Microglia and other cellular mediators of immunological dysfunction in schizophrenia: a narrative synthesis of clinical findings

KD Nguyen, A Amerio, A Aguglia, L Magnani, A Parise… - Cells, 2023 - mdpi.com
Schizophrenia is a complex psychiatric condition that may involve immune system
dysregulation. Since most putative disease mechanisms in schizophrenia have been …

Autoimmune autonomic ganglionopathy: Ganglionic acetylcholine receptor autoantibodies

N Urriola, S Adelstein - Autoimmunity Reviews, 2022 - Elsevier
Abstract Autoimmune Autonomic Ganglionopathy (AAG) is a rare immune-mediated disease
of the autonomic nervous system. The incidence of AAG is unknown and diagnosis is often …

Neuronal nicotinic acetylcholine receptor antibodies in autoimmune central nervous system disorders

M Pechlivanidou, AG Vakrakou, K Karagiorgou… - Frontiers in …, 2024 - frontiersin.org
Background Neuronal nicotinic acetylcholine receptors (nAChRs) are abundant in the
central nervous system (CNS), playing critical roles in brain function. Antigenicity of nAChRs …

Autoantibodies against acetylcholine receptors are increased in archived serum samples from patients with schizophrenia

RT McLean, E Buist, DS Clair, J Wei - Schizophrenia Research, 2024 - Elsevier
Previous studies have demonstrated that the levels of IgG against neurotransmitter receptors
are increased in patients with schizophrenia. Genome-wide association (GWA) studies of …

A study of autoantibodies against some central nervous system antigens and the il-35 serum level in schizophrenia

M Soltani, P Beshkar, K Mokhtarian… - Iranian Journal of …, 2022 - publish.kne-publishing.com
Schizophrenia (SCZ) is a debilitating mental disorder with various causes involving complex
interactions between genetic factors and environmental agents. The immune system plays a …

Absence of neuronal nicotinic acetylcholine receptor antibodies in sera and CSF from schizophrenia patients

J Tzartos, K Karagiorgou… - Schizophrenia …, 2024 - pubmed.ncbi.nlm.nih.gov
Absence of neuronal nicotinic acetylcholine receptor antibodies in sera and CSF from
schizophrenia patients Absence of neuronal nicotinic acetylcholine receptor antibodies in sera …

Immunofluorescence labeling of lipid-binding proteins CERTs to monitor lipid raft dynamics

C Giovagnoni, SM Crivelli, M Losen… - Lipid Rafts: Methods and …, 2021 - Springer
Fluorescence microscopy is a powerful and widely used tool in molecular biology. Over the
years, the discovery and development of lipid-binding fluorescent probes has established …