The hallmarks of cancer: a long non-coding RNA point of view

T Gutschner, S Diederichs - RNA biology, 2012 - Taylor & Francis
With the advent of next generation sequencing methods and progress in transcriptome
analysis, it became obvious that the human genome contains much more than just protein …

Roles of HMGA proteins in cancer

A Fusco, M Fedele - Nature Reviews Cancer, 2007 - nature.com
The high mobility group A (HMGA) non-histone chromatin proteins alter chromatin structure
and thereby regulate the transcription of several genes by either enhancing or suppressing …

Updates on cytogenetics and molecular genetics of bone and soft tissue tumors:: Ewing sarcoma and peripheral primitive neuroectodermal tumors

AA Sandberg, JA Bridge - Cancer genetics and cytogenetics, 2000 - Elsevier
Cytogenetics of Bone and Soft Tissue Tumors [1]. In view of the remarkable developments in
this field since 1994, both in the cytogenetic and particularly in the molecular genetic …

The HMGA proteins: a myriad of functions

I Cleynen, WJM Van de Ven - … journal of oncology, 2008 - spandidos-publications.com
The 'high mobility group'HMGA protein family consists of four members: HMGA1a, HMGA1b
and HMGA1c, which result from translation of alternative spliced forms of one gene and …

[HTML][HTML] Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer

R Sgarra, A Rustighi, MA Tessari, J Di Bernardo… - FEBS letters, 2004 - Elsevier
The structural characteristics of the three nuclear phosphoproteins of the high mobility group
A family are outlined and related to their participation in chromatin structure alteration in …

Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas

M Fedele, S Battista, L Kenyon, G Baldassarre… - Oncogene, 2002 - nature.com
Overexpression of the HMGA2 gene is a common feature of neoplastic cells both in
experimental and human models. Intragenic and extragenic HMGA2 rearrangements …

Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity

J Miyazawa, A Mitoro, S Kawashiri, KK Chada, K Imai - Cancer research, 2004 - AACR
Carcinoma cells of epithelial origin are predisposed to acquire a fibroblastic feature during
progression of neoplasm referred to as the epithelial-mesenchymal transition. HMGA2 is an …

The high mobility group A1 (HMGA1) transcriptome in cancer and development

TF Sumter, L Xian, T Huso, M Koo… - Current molecular …, 2016 - ingentaconnect.com
Background & Objectives: Chromatin structure is the single most important feature that
distinguishes a cancer cell from a normal cell histologically. Chromatin remodeling proteins …

High mobility group a proteins as tumor markers

P Pallante, R Sepe, F Puca, A Fusco - Frontiers in medicine, 2015 - frontiersin.org
Almost 30 years ago, overexpression of HMGA proteins was associated with malignant
phenotype of rat thyroid cells transformed with murine retroviruses. Thereafter, several …

Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer

E Kettunen, S Anttila, JK Seppänen… - Cancer genetics and …, 2004 - Elsevier
The expression patterns of cancer-related genes in 13 cases of squamous cell lung cancer
(SCC) were characterized and compared with those in normal lung tissue and 13 …