In the past decade, the asymmetric synthesis of chiral nonracemic isoquinoline alkaloids, a
family of natural products showing a wide range of structural diversity and biological and …

Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …

This Feature Article intends to provide an overview of a variety of catalytic isomerization
reactions that have been performed using well-defined transition metal hydride precatalysts …

The Pictet-Spengler reaction (PS) is one of the most direct, efficient, and variable synthetic
method for the construction of privileged pharmacophores such as tetrahydro-isoquinolines …

A five-step total synthesis of arborisidine, a caged pentacyclic monoterpene indole alkaloid,
has been accomplished in both racemic and enantioselective manners. The synthesis …

Asymmetric metal/organo relay catalysis, utilizing a metal complex and a chiral
organocatalyst in a one-pot cascade reaction, is aimed to sequentially impart activation on …

Abstract The asymmetric Pictet–Spengler reaction (PSR) with aldehydes is well known.
However, PSR involving ketones as electrophilic partners is far‐less developed. We report …

A conjugate-base-stabilized Brønsted acid facilitates catalytic enantioselective Pictet–
Spengler reactions with unmodified tryptamine. The chiral carboxylic acid catalyst is readily …

A gram-scale enantioselective total synthesis of (+)-peganumine A was accomplished in 7
steps from commercially available 6-methoxytryptamine. Key steps included (a) a …

Catalytic asymmetric reactions promoted by metal catalysts and chiral phosphoric acids
have become useful processes for the preparation of structurally diverse and complex …