[HTML][HTML] Casein kinase 1α: biological mechanisms and theranostic potential

S Jiang, M Zhang, J Sun, X Yang - Cell Communication and Signaling, 2018 - Springer
Casein kinase 1α (CK1α) is a multifunctional protein belonging to the CK1 protein family that
is conserved in eukaryotes from yeast to humans. It regulates signaling pathways related to …

Type I interferons and endoplasmic reticulum stress in health and disease

J Sprooten, AD Garg - International review of cell and molecular biology, 2020 - Elsevier
Type I interferons (IFNs) comprise of pro-inflammatory cytokines created, as well as sensed,
by all nucleated cells with the main objective of blocking pathogens-driven infections. Owing …

[HTML][HTML] IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development

IO Peshkova, T Aghayev, AR Fatkhullina… - Nature …, 2019 - nature.com
Abdominal aortic aneurysm (AAA) is a prevalent life-threatening disease, where aortic wall
degradation is mediated by accumulated immune cells. Although cytokines regulate …

[HTML][HTML] CRFB5a, a Subtype of Japanese Eel (Anguilla japonica) Type I IFN Receptor, Regulates Host Antiviral and Antimicrobial Functions through Activation of IRF3 …

T Wang, P Lin, Y Wang, X Lai, P Chen, F Li, J Feng - Animals, 2023 - mdpi.com
Simple Summary In this study, we investigated the response mechanism of type I interferon
receptor in the Japanese eel (Anguilla japonica) after an immune challenge, and we also …

Down-regulation of ID2-AS1 alleviates the neuronal injury induced by 1-Methy1-4-Phenylpyridinium in Human Neuroblastoma cell line SH-SY5Y cells through …

F Xu, H Wang, J Tian, H Xu - Neurochemical Research, 2021 - Springer
We aimed to illustrate the roles and molecular mechanisms of ID2-AS1 in parkinson's
disease (PD). Methods: qRT-PCR detected the expression of ID2-AS1. CCK-8, LDH release …

A new subtype of type I IFN receptor, CRFB5b, plays an active role in host antiviral and antibacterial functions in Japanese eel (Anguilla japonica)

T Wang, P Lin, Y Wang, X Lai, P Chen, F Li… - Aquaculture …, 2023 - Springer
Abstract IFNAR1 (type I IFN receptor) plays a crucial role in mammalian host immunity
against virus invasion. However, the immune function of the fish teleost IFNAR1, which is …

The PKR-like endoplasmic reticulum kinase promotes the dissemination of Myc-induced leukemic cells

J Gui, KV Katlinski, C Koumenis, JA Diehl… - Molecular Cancer …, 2019 - AACR
Hyperactive oncogenic Myc stimulates protein synthesis that induces the unfolded protein
response, which requires the function of the eukaryotic translation initiation factor 2-alpha …

[HTML][HTML] 基于文献计量的国外干细胞研究热点主题分析

张庆, 田芳慧 - 济宁医学院学报, 2020 - jnyxy.cnjournals.org
目的揭示干细胞领域的研究现状, 探究该领域已发表文献的特征, 内部关系,
主题发展趋势及其知识结构, 为研究人员提供参考. 方法以PubMed 中收录的干细胞相关文献 …

[PDF][PDF] Der Einfluss einer HIV-Infektion und der Stimulation von Typ I Interferon auf die Expression des Interferon-Rezeptors

J Ickler - 2020 - duepublico2.uni-due.de
Bei Retroviren handelt es sich um behüllte RNA Viren mit einzelsträngigem Genom positiver
Polarität von 7-12 kb. Zu der Familie der Retroviridae gehören die Unterfamilien …

IL-27 receptor signaling regulated stress myelopoiesis drives Abdominal Aortic Aneurysm development

IO Peshkova, T Aghayev, AR Fatkhullina, P Makhov… - bioRxiv, 2019 - biorxiv.org
Abstract Abdominal Aortic Aneurysm (AAA) is a vascular disease, where aortic wall
degradation is mediated by accumulated immune cells. Though cytokines regulate the …