Cisplatin is a bedrock of cancer management and one of the most used chemotherapeutic
agents in the treatment of germ cell, lung, bladder, ovarian, and head and neck cancers …

Introduction Ototoxicity associated with platinum-based chemotherapy is highly prevalent
and can cause detrimental consequences among cancer survivors. Discussion In this article …

Objective: To determine the efficacy of long-term high-dose intratympanic dexamethasone in
protecting the hearing capacity of cancer patients undergoing cisplatin-based ototoxic …

Hearing damage is one of the main toxic effects of platinum compounds, it derives from the
irreversible degeneration of hair cells of the ear. Genetic association studies have …

Background and Objective: Cisplatin is a chemotherapy drug used to treat several types of
malignancies. It is a platinum-based compound that interferes with cell division and DNA …

Purpose Ototoxicity is a prominent side effect of cisplatin-based chemotherapy. There are
few reports, however, estimating its prevalence in well-defined cohorts and associated risk …

Background Cisplatin, a first‐generation platinum agent, is used for managing various
cancers and is associated with dose‐dependent side effects of hearing impairment and …

Introduction Robust clinically relevant epidemiological and audiological data are needed to
prepare for future clinical trials aiming at preventing cisplatin-induced ototoxicity in this …

Introduction Considering that previous studies suggest that pesticides may cause hearing
disorders in humans, as well as the lack of studies proving the specific mechanisms of injury …

Background: The most common complaint of patients affected by chemotherapy-induced
hearing loss is difficulty understanding speech in noisy environments despite the use of …