Influenza viruses, including four major types (A, B, C, and D), can cause mild-to-severe and
lethal diseases in humans and animals. Influenza viruses evolve rapidly through antigenic …

Influenza viruses cause epidemics and pandemics. Like all viruses, influenza viruses rely on
the host cellular machinery to support their life cycle. Accordingly, identification of the host …

ABSTRACT A novel human coronavirus (HCoV-EMC) was recently identified in the Middle
East as the causative agent of a severe acute respiratory syndrome (SARS) resembling the …

Curcumin (diferuloylmethane) is a widely used spice and colouring agent in food.
Accumulated evidence indicates that curcumin is associated with a great variety of …

Influenza is a worldwide health and financial burden posing a significant risk to the immune-
compromised, obese, diabetic, elderly, and pediatric populations. We identified increases in …

From a panel of 22 flavonoids, we identified six compounds (apigenin, baicalein, biochanin
A, kaempferol, luteolin, naringenin) that inhibited influenza A nucleoprotein production in …

Influenza viruses are major human pathogens responsible for respiratory diseases affecting
millions of people worldwide and characterized by high morbidity and significant mortality …

Influenza A virus (IAV) infection could induce autophagosome accumulation. However, the
impact of the autophagy machinery on IAV infection remains controversial. Here, we showed …

Background Influenza is a common infectious disease caused by influenza viruses. Annual
epidemics cause severe illnesses, deaths, and economic loss around the world. To better …

The phosphoinositide-3 kinase (PI3K) pathway regulates diverse cellular activities related to
cell growth, migration, survival, and vesicular trafficking. It is known that Ebola virus requires …