Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

The role of non-coding RNAs in extracellular vesicles in breast cancer and their diagnostic implications

M Samuels, W Jones, B Towler, C Turner, S Robinson… - Oncogene, 2023 - nature.com
Breast Cancer (BC) is the most common form of cancer worldwide, responsible for 25% of
cancers in women. Whilst treatment is effective and often curative in early BC, metastatic …

Identification of a six‐microRNA signature as a potential diagnostic biomarker in breast cancer tissues

M Mahmoudian, E Razmara… - Journal of clinical …, 2021 - Wiley Online Library
Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …

Nutraceuticals in the Mediterranean diet: potential avenues for breast cancer treatment

G Augimeri, FI Montalto, C Giordano, I Barone… - Nutrients, 2021 - mdpi.com
The traditional Mediterranean Diet constitutes a food model that refers to the dietary patterns
of the population living in countries bordering the Mediterranean Sea in the early 1960s. A …

[HTML][HTML] Extracellular vesicle-mediated transport: Reprogramming a tumor microenvironment conducive with breast cancer progression and metastasis

D Brena, MB Huang, V Bond - Translational oncology, 2022 - Elsevier
Breast cancer metastatic progression to critical secondary sites is the second leading cause
of cancer-related mortality in women. While existing therapies are highly effective in …

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Emerging innovations on exosome-based onco-therapeutics

X Dai, Y Ye, F He - Frontiers in Immunology, 2022 - frontiersin.org
Exosomes, nano-sized extracellular vesicles for intercellular communications, are gaining
rapid momentum as a novel strategy for the diagnosis and therapeutics of a spectrum of …

Extracellular vesicles in breast cancer: from biology and function to clinical diagnosis and therapeutic management

S Loric, JA Denis, C Desbene, M Sabbah… - International journal of …, 2023 - mdpi.com
Breast cancer (BC) is the first worldwide most frequent cancer in both sexes and the most
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …

Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner

J Lei, X Jiang, D Huang, Y Jing, S Yang, L Geng… - Protein & …, 2024 - academic.oup.com
Abstract Hypoxia-inducible factor (HIF-1α), a core transcription factor responding to changes
in cellular oxygen levels, is closely associated with a wide range of physiological and …

Exosomes: Breast cancer-derived extracellular vesicles; recent key findings and technologies in disease progression, diagnostics, and cancer targeting

I Nakase, T Takatani-Nakase - Drug Metabolism and Pharmacokinetics, 2022 - Elsevier
Breast cancer is one of the most frequently diagnosed types of cancer in women. Metastasis,
particularly to the lungs and brain, increases mortality in breast cancer patients. Recently …