In humans, the period from term birth to∼ 2 years of age is characterized by rapid and
dynamic brain development and plays an important role in cognitive development and risk of …

Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …

Throughout infancy, childhood, and adolescence, our brains undergo remarkable changes.
Processes including myelination and synaptogenesis occur rapidly across the first 2–3 years …

Technological and methodological innovations are equipping researchers with
unprecedented capabilities for detecting and characterizing pathologic processes in the …

Studying how the healthy human brain develops is important to understand early
pathological mechanisms and to assess the influence of fetal or perinatal events on later life …

White matter makes up about fifty percent of the human brain. Maturation of white matter
accompanies biological development and undergoes the most dramatic changes during …

Abstract Properties of human brain tissue change across the lifespan. Here we model these
changes in the living human brain by combining quantitative magnetic resonance imaging …

Dynamic macrostructural and microstructural changes take place from the mid-fetal stage to
2 years after birth. Delineating structural changes of the brain during early development …

Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

Throughout early neurodevelopment, myelination helps provide the foundation for brain
connectivity and supports the emergence of cognitive and behavioral functioning. Early life …