Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium

CC Konkankit, SC Marker, KM Knopf, JJ Wilson - Dalton Transactions, 2018 - pubs.rsc.org
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?

JA Stubbe, DG Nocera, CS Yee, MCY Chang - Chemical reviews, 2003 - ACS Publications
Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to
deoxynucleotides in all organisms (eq 1). 1-3 These enzymes play an essential role in DNA …

Proton-coupled electron flow in protein redox machines

JL Dempsey, JR Winkler, HB Gray - Chemical reviews, 2010 - ACS Publications
Electron transfer (ET) reactions are fundamental steps in biological redox processes.
Respiration is a case in point: at least 15 ET reactions are required to take reducing …

Synthesis and evaluation of technetium-99m-and rhenium-labeled inhibitors of the prostate-specific membrane antigen (PSMA)

SR Banerjee, CA Foss, M Castanares… - Journal of medicinal …, 2008 - ACS Publications
The prostate-specific membrane antigen (PSMA) is increasingly recognized as a viable
target for imaging and therapy of cancer. We prepared seven 99mTc/Re-labeled compounds …

Photochemistry and photophysics of coordination compounds: rhenium

RA Kirgan, BP Sullivan, DP Rillema - Photochemistry and Photophysics of …, 2007 - Springer
This review describes recent advances in the photochemistry of complexes of the element
rhenium. It covers not only fundamental chemistry but the recent applications of these …

Switching the redox mechanism: models for proton-coupled electron transfer from tyrosine and tryptophan

M Sjödin, S Styring, H Wolpher, Y Xu… - Journal of the …, 2005 - ACS Publications
The coupling of electron and proton transfer is an important controlling factor in radical
proteins, such as photosystem II, ribinucleotide reductase, cytochrome oxidases, and DNA …

Ultrafast Excited-State Dynamics of Rhenium(I) Photosensitizers [Re(Cl)(CO)3(N,N)] and [Re(imidazole)(CO)3(N,N)]+: Diimine Effects

A El Nahhas, C Consani… - Inorganic …, 2011 - ACS Publications
Femto-to picosecond excited-state dynamics of the complexes [Re (L)(CO) 3 (N, N)] n (N, N=
bpy, phen, 4, 7-dimethyl-phen (dmp); L= Cl, n= 0; L= imidazole, n= 1+) were investigated …

[HTML][HTML] Proton-coupled electron transfer: a unifying mechanism for biological charge transport, amino acid radical initiation and propagation, and bond making …

CJ Chang, MCY Chang, NH Damrauer… - Biochimica et Biophysica …, 2004 - Elsevier
Redox-driven proton pumps, radical initiation and propagation in biology, and small-
molecule activation processes all involve the coupling of electron transfer to proton …

Biological inorganic chemistry at the beginning of the 21st century

HB Gray - Proceedings of the National Academy of …, 2003 - National Acad Sciences
Advances in bioinorganic chemistry since the 1970s have been driven by three factors: rapid
determination of high-resolution structures of proteins and other biomolecules, utilization of …

Electron Tunneling in Single Crystals of Pseudomonas aeruginosa Azurins

BR Crane, AJ Di Bilio, JR Winkler… - Journal of the American …, 2001 - ACS Publications
Rates of reduction of Os (III), Ru (III), and Re (I)* by Cu (I) in His83-modified Pseudomonas
aeruginosa azurins (M− Cu distance∼ 17 Å) have been measured in single crystals, where …