[HTML][HTML] Targeting glucose metabolism to overcome resistance to anticancer chemotherapy in breast cancer
Breast cancer (BC) is the most prevalent cancer in women. BC is heterogeneous, with
distinct phenotypical and morphological characteristics. These are based on their gene …
distinct phenotypical and morphological characteristics. These are based on their gene …
[HTML][HTML] Glucose metabolism and glucose transporters in breast cancer
E Shin, JS Koo - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Breast cancer is the most common malignancy in women worldwide and is associated with
high mortality rates despite the continuously advancing treatment strategies. Glucose is …
high mortality rates despite the continuously advancing treatment strategies. Glucose is …
[HTML][HTML] Metabolic-pathway-based subtyping of triple-negative breast cancer reveals potential therapeutic targets
Y Gong, P Ji, YS Yang, S Xie, TJ Yu, Y Xiao, ML Jin… - Cell metabolism, 2021 - cell.com
Triple-negative breast cancer (TNBC) remains an unmet medical challenge. We investigated
metabolic dysregulation in TNBCs by using our multi-omics database (n= 465, the largest to …
metabolic dysregulation in TNBCs by using our multi-omics database (n= 465, the largest to …
[HTML][HTML] Metabolic reprogramming in breast cancer and its therapeutic implications
N Gandhi, GM Das - Cells, 2019 - mdpi.com
Current standard-of-care (SOC) therapy for breast cancer includes targeted therapies such
as endocrine therapy for estrogen receptor-alpha (ERα) positive; anti-HER2 monoclonal …
as endocrine therapy for estrogen receptor-alpha (ERα) positive; anti-HER2 monoclonal …
[HTML][HTML] Metabolic plasticity in chemotherapy resistance
MA Desbats, I Giacomini, T Prayer-Galetti… - Frontiers in …, 2020 - frontiersin.org
Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death.
Thus, new strategies to deal with the evasion of drug response and to improve clinical …
Thus, new strategies to deal with the evasion of drug response and to improve clinical …
[HTML][HTML] Microbiome—microbial metabolome—cancer cell interactions in breast cancer—familiar, but unexplored
Breast cancer is a leading cause of death among women worldwide. Dysbiosis, an aberrant
composition of the microbiome, characterizes breast cancer. In this review we discuss the …
composition of the microbiome, characterizes breast cancer. In this review we discuss the …
Why all the fuss about oxidative phosphorylation (OXPHOS)?
Y Xu, D Xue, A Bankhead III… - Journal of medicinal …, 2020 - ACS Publications
Certain subtypes of cancer cells require oxidative phosphorylation (OXPHOS) to survive.
Increased OXPHOS dependency is frequently a hallmark of cancer stem cells and cells …
Increased OXPHOS dependency is frequently a hallmark of cancer stem cells and cells …
[HTML][HTML] Metabolic crosstalk in the breast cancer microenvironment
During tumorigenesis, breast tumour cells undergo metabolic reprogramming, which
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
The balance between breast cancer and the immune system: Challenges for prognosis and clinical benefit from immunotherapies
Cancer evolution is a complex process influenced by genetic factors and extracellular stimuli
that trigger signaling pathways to coordinate the continuous and dynamic interaction …
that trigger signaling pathways to coordinate the continuous and dynamic interaction …
Breast cancer, screening and diagnostic tools: All you need to know
D Barba, A León-Sosa, P Lugo, D Suquillo… - Critical reviews in …, 2021 - Elsevier
Breast cancer is one of the most frequent malignancies among women worldwide. Methods
for screening and diagnosis allow health care professionals to provide personalized …
for screening and diagnosis allow health care professionals to provide personalized …