Overweight and diabetes prevention: is a low-carbohydrate–high-fat diet recommendable?

F Brouns - European journal of nutrition, 2018 - Springer
In the past, different types of diet with a generally low-carbohydrate content (< 50–< 20
g/day) have been promoted, for weight loss and diabetes, and the effectiveness of a very low …

Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies

M Vargas-Soria, M García-Alloza… - Journal of …, 2023 - Springer
Diabetes mellitus is a heterogeneous chronic metabolic disorder characterized by the
presence of hyperglycemia, commonly preceded by a prediabetic state. The excess of blood …

Long-term high-fat diet consumption by mice throughout adulthood induces neurobehavioral alterations and hippocampal neuronal remodeling accompanied by …

H Zhuang, X Yao, H Li, Q Li, C Yang, C Wang… - Brain, behavior, and …, 2022 - Elsevier
High-fat diet (HFD) consumption is generally associated with an increased risk of cognitive
and emotional dysfunctions that constitute a sizeable worldwide health burden with …

Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice

SCBR Nakandakari, VR Munoz, GK Kuga… - Brain, Behavior, and …, 2019 - Elsevier
The consumption of saturated fatty acids is one of the leading risk factors for Alzheimer's
Disease (AD) development. Indeed, the short-term consumption of a high-fat diet (HFD) is …

[HTML][HTML] Western diet consumption during development: setting the stage for neurocognitive dysfunction

L Tsan, L Décarie-Spain, EE Noble… - Frontiers in …, 2021 - frontiersin.org
The dietary pattern in industrialized countries has changed substantially over the past
century due to technological advances in agriculture, food processing, storage, marketing …

Inflammation and insulin resistance as risk factors and potential therapeutic targets for Alzheimer's disease

A Vinuesa, C Pomilio, A Gregosa… - Frontiers in …, 2021 - frontiersin.org
Overnutrition and modern diets containing high proportions of saturated fat are among the
major factors contributing to a low-grade state of inflammation, hyperglycemia and …

The impact of obesity and hypercaloric diet consumption on anxiety and emotional behavior across the lifespan

KD Baker, A Loughman, SJ Spencer… - … & Biobehavioral Reviews, 2017 - Elsevier
Obesity is an increasing problem in young people. Childhood obesity and overweight have
increased rapidly on a global scale, and have tripled in the past 30 years, to affect …

Early exposure to a high-fat diet impacts on hippocampal plasticity: implication of microglia-derived exosome-like extracellular vesicles

A Vinuesa, M Bentivegna, G Calfa, F Filipello… - Molecular …, 2019 - Springer
Adolescence is a transitional period from childhood to adulthood characterized by puberty
and brain maturation involving behavioral changes and environmental vulnerability. Diet is …

Acute exposure to a high-fat diet in juvenile male rats disrupts hippocampal-dependent memory and plasticity through glucocorticoids

T Khazen, OA Hatoum, G Ferreira, M Maroun - Scientific reports, 2019 - nature.com
The limbic circuit is still undergoing maturation during juvenility and adolescence, explaining
why environmental and metabolic challenges during these developmental periods can have …

Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention

W Fakih, R Zeitoun, I AlZaim, AH Eid, F Kobeissy… - …, 2022 - Wiley Online Library
The metabolic syndrome comprises a family of clinical and laboratory findings, including
insulin resistance, hyperglycemia, hypertriglyceridemia, low high‐density lipoprotein …