The development of the three-dimensional (3D) exoscope is a marvel of technological
innovation in modern surgical practice. While its predecessor, the operating microscope …

Abstract Malignant Peripheral Nerve Sheath Tumors (MPNSTs) are rare tumors that often
occur in patients with neurofibromatosis 1. Surgical resection represents the mainstay of …

Involvement of the peripheral nervous system (PNS) is common in patients with cancer and
any part, including motor neurons, sensory ganglia, nerve roots, plexuses, cranial and …

Abstract Learning Objectives After completing this course, the reader will be able to:
Describe phenotypic and clinical features associated with neurofibromatosis 1. Identify …

Malignant peripheral nerve sheath tumors (MPNSTs) arising from cranial nerves or their
branches are very uncommon. The literature consists mainly of isolated case reports and …

Patients with bilateral vestibular schwannomas associated with neurofibromatosis type 2
(NF2) experience significant morbidity such as complete hearing loss. We have recently …

BACKGROUND: We describe the presentation, diagnostic pathway, and management of 28
patients with benign retroperitoneal schwannomas. METHODS: A prospectively kept soft …

OBJECTIVE. Schwannomas are typically benign tumors that occur sporadically, in
neurofibromatosis type 2 (NF2), or in an entity called “schwannomatosis.” Schwannomatosis …

Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft tissue sarcomas that arise
predominantly from Schwann cells. Despite the fact that MPNSTs have high local recurrence …

Abstract Neurofibromatosis type 2 (NF2) is an autosomal-dominant multiple neoplasia
syndrome that results from mutations in the NF2 tumor suppressor gene. Patients with NF2 …