Association mapping in plants in the post-GWAS genomics era
PK Gupta, PL Kulwal, V Jaiswal - Advances in genetics, 2019 - Elsevier
With the availability of DNA-based molecular markers during early 1980s and that of
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …
Genome‐wide association studies on the phyllosphere microbiome: embracing complexity in host–microbe interactions
Environmental sequencing shows that plants harbor complex communities of microbes that
vary across environments. However, many approaches for mapping plant genetic variation …
vary across environments. However, many approaches for mapping plant genetic variation …
Environment dominates over host genetics in shaping human gut microbiota
Human gut microbiome composition is shaped by multiple factors but the relative
contribution of host genetics remains elusive. Here we examine genotype and microbiome …
contribution of host genetics remains elusive. Here we examine genotype and microbiome …
Iterative usage of fixed and random effect models for powerful and efficient genome-wide association studies
False positives in a Genome-Wide Association Study (GWAS) can be effectively controlled
by a fixed effect and random effect Mixed Linear Model (MLM) that incorporates population …
by a fixed effect and random effect Mixed Linear Model (MLM) that incorporates population …
Genome-and transcriptome-wide association studies provide insights into the genetic basis of natural variation of seed oil content in Brassica napus
Seed oil content (SOC) is a highly important and complex trait in oil crops. Here, we
decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and …
decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and …
Sparse whole-genome sequencing identifies two loci for major depressive disorder
Nature, 2015 - nature.com
Major depressive disorder (MDD), one of the most frequently encountered forms of mental
illness and a leading cause of disability worldwide, poses a major challenge to genetic …
illness and a leading cause of disability worldwide, poses a major challenge to genetic …
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites
T Long, M Hicks, HC Yu, WH Biggs, EF Kirkness… - Nature …, 2017 - nature.com
Genetic factors modifying the blood metabolome have been investigated through genome-
wide association studies (GWAS) of common genetic variants and through exome …
wide association studies (GWAS) of common genetic variants and through exome …
A fast and agnostic method for bacterial genome-wide association studies: Bridging the gap between k-mers and genetic events
Genome-wide association study (GWAS) methods applied to bacterial genomes have
shown promising results for genetic marker discovery or detailed assessment of marker …
shown promising results for genetic marker discovery or detailed assessment of marker …
Metabolite‐based genome‐wide association study enables dissection of the flavonoid decoration pathway of wheat kernels
J Chen, X Hu, T Shi, H Yin, D Sun… - Plant Biotechnology …, 2020 - Wiley Online Library
The marriage of metabolomic approaches with genetic design has proven a powerful tool in
dissecting diversity in the metabolome and has additionally enhanced our understanding of …
dissecting diversity in the metabolome and has additionally enhanced our understanding of …
Natural selection of a GSK3 determines rice mesocotyl domestication by coordinating strigolactone and brassinosteroid signaling
S Sun, T Wang, L Wang, X Li, Y Jia, C Liu… - Nature …, 2018 - nature.com
Mesocotyl is the crucial organ for pushing buds out of deep water or soil after germination in
monocots. Deep direct seeding or mechanized dry seeding cultivation practice requires rice …
monocots. Deep direct seeding or mechanized dry seeding cultivation practice requires rice …