Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …

A great deal of information is known regarding the process of sex differentiation in fish, and
the mechanisms involved in primary sex determination are now beginning to be defined. A …

This award-winning classic examines the construction of sexual identity in biology, society,
and history. Why do some people prefer heterosexual love while others fancy the same sex …

Human genomes are 99.9 percent identical—with one prominent exception. Instead of a
matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome …

Reproduction is required for the survival of all mammalian species, and thousands of
essential'sex'genes are conserved through evolution. Basic research helps to define these …

The mammalian Y chromosome acts as a dominant male determinant as a result of the
action of a single gene, Sry, whose role in sex determination is to initiate testis rather than …

Arguably the most defining moment in our lives is fertilization, the point at which we inherit
either an X or a Y chromosome from our father. The profoundly different journeys of male …

The pivotal point of vertebrate sex determination is the development of the gonad into a
testis or ovary, which governs phenotypic sex through the production of hormones. The …

Sex-specific gonadal development starts with formation of the bipotential gonad, which then
differentiates into either a mature testis or an ovary. This process is dependent on activation …

A newborn infant with ambiguous genitalia is a complex enough problem to unravel without
any further clouding by confusing terms. The nomenclature 'intersex','hermaphrodite'and …