Individuals who maintain cognitive function despite high levels of Alzheimer's disease (AD)-
associated pathology are said to be 'resilient'to AD. Identifying mechanisms underlying …

Background In recent years, much evidence has emerged to indicate that exercise can
benefit people when performed properly. This review summarizes the exercise interventions …

Identifying appropriate animal models is critical in developing translatable in vitro and in vivo
systems for therapeutic drug development and investigating disease pathophysiology …

Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Environmental enrichment (EE) is an experimental paradigm that is used to explore how a
complex, stimulating environment can impact overall health. In laboratory animal …

Alzheimer's disease (AD) is the main neurodegenerative disorder characterized by several
pathophysiological features, including the misfolding of the tau protein and the amyloid beta …

Alzheimer's disease (AD) is a severe and progressive neurodegenerative condition that
exerts detrimental effects on brain function. As of now, there is no effective treatment for AD …

Neurodegenerative disease encompasses a wide range of disorders afflicting the central
and peripheral nervous systems and is a major unmet biomedical need of our time. There …

With the aging of the world population, there has been a notable increase in the incidence of
Alzheimer disease (AD), the most prevalent neurodegenerative disease affecting the elderly …

Exercise exerts a beneficial effect on the major pathological and clinical symptoms
associated with Alzheimer's disease in humans and mouse models of the disease. While …