Centrifugal microfluidic platforms: advanced unit operations and applications

O Strohmeier, M Keller, F Schwemmer… - Chemical Society …, 2015 - pubs.rsc.org
Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic
companies either have products on the market or are currently evaluating centrifugal …

CD-based microfluidics for primary care in extreme point-of-care settings

S Smith, D Mager, A Perebikovsky, E Shamloo… - Micromachines, 2016 - mdpi.com
We review the utility of centrifugal microfluidic technologies applied to point-of-care
diagnosis in extremely under-resourced environments. The various challenges faced in …

Lab-on-a-CD: A fully integrated molecular diagnostic system

LX Kong, A Perebikovsky, J Moebius… - Journal of …, 2016 - journals.sagepub.com
The field of centrifugal microfluidics has experienced tremendous growth during the past 15
years, especially in applications such as lab-on-a-disc (LoD) diagnostics. The strength of …

Review on pneumatic operations in centrifugal microfluidics

JF Hess, S Zehnle, P Juelg, T Hutzenlaub, R Zengerle… - Lab on a Chip, 2019 - pubs.rsc.org
Centrifugal microfluidics allows for miniaturization, automation and parallelization of
laboratory workflows. The fact that centrifugal forces are always directed radially outwards …

Label-free, spatially multiplexed SPR detection of immunoassays on a highly integrated centrifugal Lab-on-a-Disc platform

CM Miyazaki, DJ Kinahan, R Mishra… - Biosensors and …, 2018 - Elsevier
As a direct, label-free method, Surface Plasmon Resonance (SPR) detection significantly
reduces the needs for liquid handling and reagent storage compared to common enzyme …

Systematic review of centrifugal valving based on digital twin modeling towards highly integrated lab-on-a-disc systems

J Ducrée - Microsystems & nanoengineering, 2021 - nature.com
Current, application-driven trends towards larger-scale integration (LSI) of microfluidic
systems for comprehensive assay automation and multiplexing pose significant …

A novel method for inward fluid displacement in centrifugal microdevices for highly integrated nucleic acid processing with long-term reagent storage

LM Dignan, SM Karas, IK Mighell, WR Treene… - Analytica Chimica …, 2022 - Elsevier
Rotationally-driven lab-on-a-disc (LoaD) microfluidic systems are among the most promising
methods for realizing complex nucleic acid (NA) testing at the point-of-need (PoN). However …

The effect of moment of inertia on the liquids in centrifugal microfluidics

E Pishbin, M Eghbal, S Fakhari, A Kazemzadeh… - Micromachines, 2016 - mdpi.com
The flow of liquids in centrifugal microfluidics is unidirectional and dominated by centrifugal
and Coriolis forces (ie, effective only at T-junctions). Developing mechanisms and …

System-level network simulation for robust centrifugal-microfluidic lab-on-a-chip systems

I Schwarz, S Zehnle, T Hutzenlaub, R Zengerle… - Lab on a Chip, 2016 - pubs.rsc.org
Centrifugal microfluidics shows a clear trend towards a higher degree of integration and
parallelization. This trend leads to an increase in the number and density of integrated …

Dissolvable film-controlled buoyancy pumping and aliquoting on a lab-on-a-disc

NA Kilcawley, TC Voebel, PL Early, NA McArdle… - Processes, 2023 - mdpi.com
Lab-on-a-Disc (LoaD) has great potential for applications in decentralised bioanalytical
testing where speed and robustness are critical. Here, a disc-shaped microfluidic chip is …