Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …

Flexibly selecting appropriate actions in response to complex, ever-changing environments
requires both cortical and subcortical regions, which are typically described as participating …

Working memory—the brain's ability to internalize information and use it flexibly to guide
behaviour—is an essential component of cognition. Although activity related to working …

Behavior relies on activity in structured neural circuits that are distributed across the brain,
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …

Motor behaviors are often planned long before execution but only released after specific
sensory events. Planning and execution are each associated with distinct patterns of motor …

Neural mechanisms of perceptual decision making have been extensively studied in
experimental settings that mimic stable environments with repeating stimuli, fixed rules, and …

A surprising finding of recent studies in mouse is the dominance of widespread movement-
related activity throughout the brain, including in early sensory areas. In awake subjects …

Action selection occurs through competition between potential choice options. Neural
correlates of choice competition are observed across frontal cortex and downstream …

Decision-making requires flexibility to rapidly switch one's actions in response to sensory
stimuli depending on information stored in memory. We identified cortical areas and neural …

To localize objects during active sensing, animals must differentiate stimuli caused by
volitional movement from real-world object motion. To determine a neural basis for this …