Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …

This review covers some of the recent progress in the field of peptide antibiotics with a focus
on compounds with novel or established mode of action and with demonstrated efficacy in …

Covering: up to fall 2022. Nonribosomal peptide synthetases (NRPSs) are a family of
modular, multidomain enzymes that catalyze the biosynthesis of important peptide natural …

Nonribosomal peptides are microbial secondary metabolites exhibiting a tremendous
structural diversity and a broad range of biological activities useful in the medical and agro …

Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …

Antimicrobial resistance is a serious threat to human health worldwide, prompting research
efforts on a massive scale in search of novel antibiotics to fill an urgent need for a remedy …

The discovery of antibiotics has led to the effective treatment of bacterial infections that were
otherwise fatal and has had a transformative effect on modern medicine. Teixobactin is an …

Many biologically active natural products are synthesized by nonribosomal peptide
synthetases (NRPSs), polyketide synthases (PKSs) and their hybrids. These …

Cyclic depsipeptides are an important class of peptide natural products that are defined by
the presence of ester and amide bonds within the macrocycle. The structural diversity of …

Discovering new antibiotics with novel chemical scaffolds and antibacterial mechanisms
presents a challenge for medicinal scientists worldwide as the ever‐increasing bacterial …