A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …

Microbes are the leading producers of useful natural products. Natural products from
microbes and plants make excellent drugs. Significant portions of the microbial genomes are …

Natural products and their derivatives play an important role in modern healthcare as
frontline treatments for many diseases and as inspiration for chemically synthesized …

Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

During the last decades, biocatalysis became of increasing importance for chemical and
pharmaceutical industries. Regarding regio-and stereospecificity, enzymes have shown to …

As a promising one-carbon renewable substrate for industrial biotechnology, methanol has
attracted much attention. However, engineering of microorganisms for industrial production …

Statins are a group of extremely successful drugs that lower cholesterol levels in blood;
decreasing the risk of heath attack or stroke. In recent years, statins have also been reported …

Although biotin is an essential enzyme cofactor found in all three domains of life, our
knowledge of its biosynthesis remains fragmentary. Most of the carbon atoms of biotin are …

Biotin is an enzyme cofactor indispensable to metabolic fixation of carbon dioxide in all three
domains of life. Although the catalytic and physiological roles of biotin have been well …

Direct and regiospecific amino‐functionalization of non‐activated carbon could be achieved
using one recombinant microbial catalyst. The presented proof of concept shows that …