Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

Abstract Coronavirus disease-19 (COVID-19), a devastating respiratory illness caused by
SARS-associated coronavirus-2 (SARS-CoV-2), has already affected over 64 million people …

Cytokines are small secreted proteins released by different types of cells with specific effects
on cellular signaling and communication via binding to their receptors on the cell surface. IL …

In this review, we discuss the importance of capsaicin to the current understanding of
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …

Curcumin is a naturally occurring polyphenol that is isolated from the rhizome of Curcuma
longa (turmeric). This medicinal compound has different biological activities, including …

Naringenin is a flavonoid widely consumed by humans that present anti-inflammatory
activity and low toxicity. Recently, the analgesic effect of naringenin has been demonstrated …

Despite the progress that has occurred in recent years in the development of therapies to
treat painful and inflammatory diseases, there is still a need for effective and potent …

Oxidative stress can be induced by various stimuli and altered in certain conditions,
including exercise and pain. Although many studies have investigated oxidative stress in …

Background: Pathological pain conditions can be triggered after peripheral nerve injury
and/or inflammation. It is a major clinical problem that is poorly treated with available …

Background and Purpose Maresin 1 (MaR1) is a specialised pro‐resolving lipid mediator
with anti‐inflammatory and analgesic activities. In this study, we addressed the modulation …