The changing face of gastric cancer: epidemiologic trends and advances in novel therapies

R Chandra, N Balachandar, S Wang, S Reznik… - Cancer Gene …, 2021 - nature.com
Gastric cancer is an aggressive solid-tumor malignancy with poor prognosis. The
epidemiologic face of gastric cancer is changing and further insight into its heterogenous …

A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers

A Fatehullah, Y Terakado, S Sagiraju, TL Tan… - Nature Cell …, 2021 - nature.com
Gastric cancer is among the most prevalent and deadliest of cancers globally. To derive
mechanistic insight into the pathways governing this disease, we generated a Claudin18 …

The emerging role of MMP12 in the oral environment

B Lin, HL Ser, L Wang, J Li, KG Chan, LH Lee… - International Journal of …, 2023 - mdpi.com
Matrix metalloproteinase-12 (MMP12), or macrophage metalloelastase, plays important
roles in extracellular matrix (ECM) component degradation. Recent reports show MMP12 …

Berberine attenuated proliferation, invasion and migration by targeting the AMPK/HNF4α/WNT5A pathway in gastric carcinoma

Q Hu, L Li, X Zou, L Xu, P Yi - Frontiers in pharmacology, 2018 - frontiersin.org
Background: Recent epidemiologic studies have found that patients with diabetes have a
higher risk of gastric cancer (GC), and the long-term use of metformin is associated with a …

A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer

Q Shen, K Polom, C Williams, FMS de Oliveira… - …, 2019 - thelancet.com
Background Gastric cancer (GC) is the third leading cause of cancer death. Early detection
is a key factor to reduce its mortality. Methods We retrospectively collected pre-and …

[HTML][HTML] miR‑508‑3p suppresses the development of ovarian carcinoma by targeting CCNA2 and MMP7

F Guo, K Zhang, M Li, L Cui, G Liu… - International …, 2020 - spandidos-publications.com
Ovarian cancer is the most lethal gynecological tumor, and the 5‑year survival rate is only~
40%. The poor survival rate is due to cancer diagnosis at an advanced stage, when the …

Study of gene expression profiles of breast cancers in Indian women

S Malvia, SAR Bagadi, D Pradhan, C Chintamani… - Scientific reports, 2019 - nature.com
Breast cancer is the most common cancer among women globally. In India, the incidence of
breast cancer has increased significantly during the last two decades with a higher …

[HTML][HTML] Analysis of gastric cancer transcriptome allows the identification of histotype specific molecular signatures with prognostic potential

A Carino, L Graziosi, S Marchianò, M Biagioli… - Frontiers in …, 2021 - frontiersin.org
Gastric cancer is the fifth most common malignancy but the third leading cause of cancer-
associated mortality worldwide. Therapy for gastric cancer remain largely suboptimal …

Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods

C Li, X Zeng, H Yu, Y Gu, W Zhang - World journal of surgical oncology, 2018 - Springer
Background Pancreatic cancer is one of the most lethal tumors with poor prognosis, and
lacks of effective biomarkers in diagnosis and treatment. The aim of this investigation was to …

Identification of key genes and signaling pathways associated with the progression of gastric cancer

C Yu, J Chen, J Ma, L Zang, F Dong, J Sun… - Pathology & Oncology …, 2020 - Springer
Genomic features have been gradually regarded as part of the fundamentals to the clinical
diagnosis and treatment for gastric cancer. However, the molecular alterations taking place …