The changing face of gastric cancer: epidemiologic trends and advances in novel therapies
Gastric cancer is an aggressive solid-tumor malignancy with poor prognosis. The
epidemiologic face of gastric cancer is changing and further insight into its heterogenous …
epidemiologic face of gastric cancer is changing and further insight into its heterogenous …
A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers
A Fatehullah, Y Terakado, S Sagiraju, TL Tan… - Nature Cell …, 2021 - nature.com
Gastric cancer is among the most prevalent and deadliest of cancers globally. To derive
mechanistic insight into the pathways governing this disease, we generated a Claudin18 …
mechanistic insight into the pathways governing this disease, we generated a Claudin18 …
The emerging role of MMP12 in the oral environment
Matrix metalloproteinase-12 (MMP12), or macrophage metalloelastase, plays important
roles in extracellular matrix (ECM) component degradation. Recent reports show MMP12 …
roles in extracellular matrix (ECM) component degradation. Recent reports show MMP12 …
Berberine attenuated proliferation, invasion and migration by targeting the AMPK/HNF4α/WNT5A pathway in gastric carcinoma
Q Hu, L Li, X Zou, L Xu, P Yi - Frontiers in pharmacology, 2018 - frontiersin.org
Background: Recent epidemiologic studies have found that patients with diabetes have a
higher risk of gastric cancer (GC), and the long-term use of metformin is associated with a …
higher risk of gastric cancer (GC), and the long-term use of metformin is associated with a …
A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer
Q Shen, K Polom, C Williams, FMS de Oliveira… - …, 2019 - thelancet.com
Background Gastric cancer (GC) is the third leading cause of cancer death. Early detection
is a key factor to reduce its mortality. Methods We retrospectively collected pre-and …
is a key factor to reduce its mortality. Methods We retrospectively collected pre-and …
[HTML][HTML] miR‑508‑3p suppresses the development of ovarian carcinoma by targeting CCNA2 and MMP7
F Guo, K Zhang, M Li, L Cui, G Liu… - International …, 2020 - spandidos-publications.com
Ovarian cancer is the most lethal gynecological tumor, and the 5‑year survival rate is only~
40%. The poor survival rate is due to cancer diagnosis at an advanced stage, when the …
40%. The poor survival rate is due to cancer diagnosis at an advanced stage, when the …
Study of gene expression profiles of breast cancers in Indian women
S Malvia, SAR Bagadi, D Pradhan, C Chintamani… - Scientific reports, 2019 - nature.com
Breast cancer is the most common cancer among women globally. In India, the incidence of
breast cancer has increased significantly during the last two decades with a higher …
breast cancer has increased significantly during the last two decades with a higher …
[HTML][HTML] Analysis of gastric cancer transcriptome allows the identification of histotype specific molecular signatures with prognostic potential
Gastric cancer is the fifth most common malignancy but the third leading cause of cancer-
associated mortality worldwide. Therapy for gastric cancer remain largely suboptimal …
associated mortality worldwide. Therapy for gastric cancer remain largely suboptimal …
Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods
Background Pancreatic cancer is one of the most lethal tumors with poor prognosis, and
lacks of effective biomarkers in diagnosis and treatment. The aim of this investigation was to …
lacks of effective biomarkers in diagnosis and treatment. The aim of this investigation was to …
Identification of key genes and signaling pathways associated with the progression of gastric cancer
Genomic features have been gradually regarded as part of the fundamentals to the clinical
diagnosis and treatment for gastric cancer. However, the molecular alterations taking place …
diagnosis and treatment for gastric cancer. However, the molecular alterations taking place …