The biofilm matrix: multitasking in a shared space

HC Flemming, ED van Hullebusch, TR Neu… - Nature Reviews …, 2023 - nature.com
The biofilm matrix can be considered to be a shared space for the encased microbial cells,
comprising a wide variety of extracellular polymeric substances (EPS), such as …

Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Selective enrichment of bacterial pathogens by microplastic biofilm

X Wu, J Pan, M Li, Y Li, M Bartlam, Y Wang - Water research, 2019 - Elsevier
Microplastics have been found to be ubiquitous in freshwater ecosystems, providing a novel
substrate for biofilm formation. Here, we incubated biofilm on microplastics and two natural …

Implant infections: adhesion, biofilm formation and immune evasion

CR Arciola, D Campoccia, L Montanaro - Nature reviews microbiology, 2018 - nature.com
Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …

Horizontal transfer of antibiotic resistance genes in clinical environments

NA Lerminiaux, ADS Cameron - Canadian journal of …, 2019 - cdnsciencepub.com
A global medical crisis is unfolding as antibiotics lose effectiveness against a growing
number of bacterial pathogens. Horizontal gene transfer (HGT) contributes significantly to …

Gastrointestinal biofilms in health and disease

JP Motta, JL Wallace, AG Buret, C Deraison… - Nature Reviews …, 2021 - nature.com
Microorganisms colonize various ecological niches in the human habitat, as they do in
nature. Predominant forms of multicellular communities called biofilms colonize human …

Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment

L Xue, N Gong, SJ Shepherd, X Xiong… - Journal of the …, 2022 - ACS Publications
The development of lipid nanoparticle (LNP) formulations for targeting the bone
microenvironment holds significant potential for nucleic acid therapeutic applications …

Biofilms: hot spots of horizontal gene transfer (HGT) in aquatic environments, with a focus on a new HGT mechanism

K Abe, N Nomura, S Suzuki - FEMS microbiology ecology, 2020 - academic.oup.com
Biofilms in water environments are thought to be hot spots for horizontal gene transfer (HGT)
of antibiotic resistance genes (ARGs). ARGs can be spread via HGT, though mechanisms …