Drivers of tuberculosis transmission

B Mathema, JR Andrews, T Cohen… - The Journal of …, 2017 - academic.oup.com
Measuring tuberculosis transmission is exceedingly difficult, given the remarkable variability
in the timing of clinical disease after Mycobacterium tuberculosis infection; incident disease …

Methods used in the spatial analysis of tuberculosis epidemiology: a systematic review

D Shaweno, M Karmakar, KA Alene, R Ragonnet… - BMC medicine, 2018 - Springer
Background Tuberculosis (TB) transmission often occurs within a household or community,
leading to heterogeneous spatial patterns. However, apparent spatial clustering of TB could …

Spatially targeted screening to reduce tuberculosis transmission in high-incidence settings

PGT Cudahy, JR Andrews, A Bilinski… - The Lancet Infectious …, 2019 - thelancet.com
As the leading infectious cause of death worldwide and the primary proximal cause of death
in individuals living with HIV, tuberculosis remains a global concern. Existing tuberculosis …

An explanation for the low proportion of tuberculosis that results from transmission between household and known social contacts

N McCreesh, RG White - Scientific reports, 2018 - nature.com
We currently have little idea where Mycobacterium tuberculosis (Mtb) transmission occurs in
high incidence settings. Molecular studies suggest that only around 8–19% of transmission …

Detection, survival and infectious potential of Mycobacterium tuberculosis in the environment: a review of the evidence and epidemiological implications

L Martinez, R Verma, J Croda… - European …, 2019 - Eur Respiratory Soc
Much remains unknown about Mycobacterium tuberculosis transmission. Seminal
experimental studies from the 1950s demonstrated that airborne expulsion of droplet nuclei …

Quantifying Mycobacterium tuberculosis Transmission Dynamics Across Global Settings: A Systematic Analysis

JP Smith, T Cohen, D Dowdy, S Shrestha… - American journal of …, 2023 - academic.oup.com
The degree to which individual heterogeneity in the production of secondary cases
(“superspreading”) affects tuberculosis (TB) transmission has not been systematically …

Blurring cluster randomized trials and observational studies: Two-Stage TMLE for subsampling, missingness, and few independent units

JR Nugent, C Marquez, ED Charlebois, R Abbott… - …, 2023 - academic.oup.com
Cluster randomized trials (CRTs) often enroll large numbers of participants; yet due to
resource constraints, only a subset of participants may be selected for outcome assessment …

The Association Between Social Network Characteristics and Tuberculosis Infection Among Adults in 9 Rural Ugandan Communities

C Marquez, Y Chen, M Atukunda… - Clinical Infectious …, 2023 - academic.oup.com
Background Social network analysis can elucidate tuberculosis transmission dynamics
outside the home and may inform novel network-based case-finding strategies. Methods We …

[HTML][HTML] Mapping sites of high TB transmission risk: integrating the shared air and social behaviour of TB cases and adolescents in a South African township

B Patterson, CD Morrow, D Kohls, C Deignan… - Science of The Total …, 2017 - Elsevier
Background Tuberculosis remains a major public health problem in poverty-stricken areas of
the world. Communal gathering places account for the majority of TB transmission in high …

Plan Beta for tuberculosis: it's time to think seriously about poorly ventilated congregate settings

TA Yates, F Tanser, I Abubakar - The International Journal of …, 2016 - ingentaconnect.com
Globally, the rates of decline in tuberculosis (TB) incidence are disappointing, but in line with
model predictions regarding the likely impact of the DOTS strategy. Here, we review …