Gadolinium deposition in the brain: summary of evidence and recommendations

V Gulani, F Calamante, FG Shellock, E Kanal… - The Lancet …, 2017 - thelancet.com
Emerging evidence has linked MRI signal changes in deep nuclei of the brain with repeated
administration of gadolinium-based contrast agents. Gadolinium deposits have been …

Gadolinium deposition in brain: current scientific evidence and future perspectives

BJ Guo, ZL Yang, LJ Zhang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
In the past 4 years, many publications described a concentration-dependent deposition of
gadolinium in the brain both in adults and children, seen as high signal intensities in the …

Gadolinium deposition in the brain: current updates

JW Choi, WJ Moon - Korean journal of radiology, 2019 - synapse.koreamed.org
Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …

Gadolinium retention in the body: what we know and what we can do

E Tedeschi, F Caranci, F Giordano, V Angelini… - La radiologia …, 2017 - Springer
Gadolinium-based contrast agents (GBCA), widely used in Magnetic Resonance Imaging
(MRI) for almost 30 years, were recently shown to be deposited in the brain and to induce …

Pediatric brain: no increased signal intensity in the dentate nucleus on unenhanced T1-weighted MR images after consecutive exposure to a macrocyclic gadolinium …

A Radbruch, R Haase, P Kickingereder, P Bäumer… - Radiology, 2017 - pubs.rsna.org
Purpose To determine the effect of at least five serial injections of the macrocyclic
gadolinium-based contrast agent (GBCA) gadoterate meglumine on the signal intensity (SI) …

Signal enhancement of the dentate nucleus at unenhanced MR imaging after very high cumulative doses of the macrocyclic gadolinium-based contrast agent …

A Bjørnerud, SAS Vatnehol, C Larsson… - Radiology, 2017 - pubs.rsna.org
Purpose To test for measurable visual enhancement of the dentate nucleus (DN) on
unenhanced T1-weighted magnetic resonance (MR) images in a cohort of patients with a …

Gadolinium deposition in the brain: a systematic review of existing guidelines and policy statement issued by the Canadian Association of Radiologists

AF Costa, CB van der Pol, PJ Maralani… - Canadian …, 2018 - journals.sagepub.com
Emerging evidence has confirmed that, following administration of a gadolinium-based
contrast agent (GBCA), very small amounts of gadolinium will deposit in the brain of humans …

A review of the current evidence on gadolinium deposition in the brain

R Pullicino, M Radon, S Biswas, M Bhojak… - Clinical Neuroradiology, 2018 - Springer
Over the past 3 years, gadolinium-based contrast agents have been linked to MRI signal
changes in the brain, which have been found to be secondary to gadolinium deposition in …

Effects of serial macrocyclic-based contrast materials gadoterate meglumine and gadobutrol administrations on gadolinium-related dentate nuclei signal increases in …

A Splendiani, M Perri, C Marsecano, V Vellucci… - La radiologia …, 2018 - Springer
Purpose To perform T1 signal intensity (SI) measurements in the dentate nuclei of adult
patients with confirmed multiple sclerosis (MS) after serial administrations of the macrocyclic …

Is there long-term signal intensity increase in the central nervous system on T1-weighted images after MR imaging with the hepatospecific contrast agent gadoxetic …

J Kahn, H Posch, IG Steffen, D Geisel, C Bauknecht… - Radiology, 2017 - pubs.rsna.org
Purpose To evaluate whether there is T1-weighted signal intensity (SI) increase in the
dentate nucleus (DN) and globus pallidus (GP) in relation to the middle cerebellar peduncle …