T cell migration in rheumatoid arthritis

M Mellado, L Martínez-Muñoz, G Cascio… - Frontiers in …, 2015 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
in joints, associated with synovial hyperplasia and with bone and cartilage destruction …

Role of CCL2/CCR2 axis in the immunopathogenesis of rheumatoid arthritis: Latest evidence and therapeutic approaches

F Moadab, H Khorramdelazad, M Abbasifard - Life Sciences, 2021 - Elsevier
Evidence suggests that uncontrolled immune system responses and their components play
a significant role in developing rheumatoid arthritis (RA), which is considered an …

Dimension-agnostic and granularity-based spatially variable gene identification using BSP

J Wang, J Li, ST Kramer, L Su, Y Chang, C Xu… - Nature …, 2023 - nature.com
Identifying spatially variable genes (SVGs) is critical in linking molecular cell functions with
tissue phenotypes. Spatially resolved transcriptomics captures cellular-level gene …

The joint synovium: a critical determinant of articular cartilage fate in inflammatory joint diseases

P Bhattaram, U Chandrasekharan - Seminars in Cell & Developmental …, 2017 - Elsevier
The synovium constitutes the envelope of articular joints and is a critical provider of synovial
fluid components and articular cartilage nutrients. Its inflammation is a predominant feature …

[HTML][HTML] Directional sensing during chemotaxis

C Janetopoulos, RA Firtel - FEBS letters, 2008 - Elsevier
Cells have the innate ability to sense and move towards a variety of chemoattractants. We
investigate the pathways by which cells sense and respond to chemoattractant gradients …

Laser light therapy in inflammatory, musculoskeletal, and autoimmune disease

VA Wickenheisser, EM Zywot, EM Rabjohns… - Current allergy and …, 2019 - Springer
Abstract Purpose of Review The goal of this review is to summarize the field to date and to
discuss strengths and limitations of low-level laser (light) therapy (LLLT) for the future …

The therapeutic potential of plant flavonoids on rheumatoid arthritis

SD Hughes, N Ketheesan… - Critical reviews in food …, 2017 - Taylor & Francis
Rheumatoid arthritis (RA) is an autoimmune condition that mainly affects peripheral joints.
Although immunosuppressive drugs and non-steroidal anti-inflammatory drugs (NSAIDs) …

Natural therapies of the inflammatory bowel disease: the case of rutin and its aglycone, quercetin

S Habtemariam, A Belai - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
Inflammatory bowel disease (IBD), commonly represented by ulcerative colitis and Crohn's
disease, is a form of chronic inflammatory disorders of the gastrointestinal system. Its current …

Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints

K Polzer, D Baeten, A Soleiman, J Distler… - Annals of the …, 2008 - ard.bmj.com
Objective: To investigate the presence and regulation of lymphatic vessels in inflamed joints
of mice with experimental arthritis as well as patients with rheumatoid arthritis (RA) and …

Diverse sensitivity thresholds in dynamic signaling responses by social amoebae

CJ Wang, A Bergmann, B Lin, K Kim, A Levchenko - Science signaling, 2012 - science.org
The complex transition from a single-cell to a multicellular life form during the formation of a
fruiting body by the amoeba Dictyostelium discoideum is accompanied by a pulsatile …