Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
G Trinchieri - Annual review of immunology, 1995 - annualreviews.org
Interleukin-12 (IL-12) is a heterodimeric cytokine produced mostly by phagocytic cells in
response to bacteria, bacterial products, and intracellular parasites, and to some degree by …
response to bacteria, bacterial products, and intracellular parasites, and to some degree by …
The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses
MK Gately, LM Renzetti, J Magram… - Annual review of …, 1998 - annualreviews.org
▪ Abstract Interleukin-12 (IL-12) is a heterodimeric cytokine that plays a central role in
promoting type 1 T helper cell (Th1) responses and, hence, cell-mediated immunity. Its …
promoting type 1 T helper cell (Th1) responses and, hence, cell-mediated immunity. Its …
[PDF][PDF] Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic …
G Trinchieri - 1994 - Citeseer
P HAGOCYTIC CELLS and natural killer (NK) cells are among the effector cell types of
innate resistance that represent a first line of defense against infections or foreign …
innate resistance that represent a first line of defense against infections or foreign …
Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives
C Dosiou, LC Giudice - Endocrine reviews, 2005 - academic.oup.com
The endocrine system and the immune system interact closely during implantation and
maintenance of pregnancy. One of the most striking examples of this communication is at the …
maintenance of pregnancy. One of the most striking examples of this communication is at the …
Interleukin-12: a cytokine at the interface of inflammation and immunity
G Trinchieri - Advances in immunology, 1998 - Elsevier
Publisher Summary Although interleukin-12 (IL-12) has been discovered only relatively
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …
Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.
CM Bacon, DW McVicar, JR Ortaldo… - The Journal of …, 1995 - europepmc.org
Abstract Interleukin (IL-12) has many effects on the function of natural killer and T cells, and
is important in the control of cell-mediated immunity. IL-2 and IL-12 display many similar …
is important in the control of cell-mediated immunity. IL-2 and IL-12 display many similar …
[图书][B] Human implantation: cell biology and immunology
YW Loke, A King - 1995 - books.google.com
This book explains and reviews some of the significant events involved in human
implantation and the establishment of the placenta in the uterus. This critical phase in …
implantation and the establishment of the placenta in the uterus. This critical phase in …
Interleukin-12
MJ Brunda - Journal of Leucocyte Biology, 1994 - academic.oup.com
Abstract Interleukin-12 (IL-12) is a newly characterized cytokine that has a unique
heterodimeric structure. It was initially cloned from B lymphoblastoid cell lines, but the …
heterodimeric structure. It was initially cloned from B lymphoblastoid cell lines, but the …
Cooperation of natural killer cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and …
M Aste-Amezaga, A D'Andrea, M Kubin, G Trinchieri - Cellular immunology, 1994 - Elsevier
The ability of natural killer cell stimulatory factor/interleukin-12 (IL-12) to induce cytokines
other than IFN-γ from both T and NK cells was studied. Both the direct effect of IL-12 and the …
other than IFN-γ from both T and NK cells was studied. Both the direct effect of IL-12 and the …
Screening for cytokine messenger ribonucleic acids in purified human decidual lymphocyte populations by the reverse-transcriptase polymerase chain reaction.
PP Jokhi, A King, AM Sharkey, SK Smith… - Journal of immunology …, 1994 - journals.aai.org
At the time of human embryo implantation, large numbers of maternal CD56brightCD16-NK
cells appear in the uterus. These unusual lymphocytes are believed to control the migration …
cells appear in the uterus. These unusual lymphocytes are believed to control the migration …