Systemic complications of acromegaly and the impact of the current treatment landscape: an update
MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …
increased mortality when not adequately treated. Substantial advances in acromegaly …
Growth hormone (GH) and cardiovascular system
This review describes the positive effects of growth hormone (GH) on the cardiovascular
system. We analyze why the vascular endothelium is a real internal secretion gland, whose …
system. We analyze why the vascular endothelium is a real internal secretion gland, whose …
Does ceruloplasmin defend against neurodegenerative diseases?
B Wang, XP Wang - Current neuropharmacology, 2019 - ingentaconnect.com
Ceruloplasmin (CP) is the major copper transport protein in plasma, mainly produced by the
liver. Glycosylphosphatidylinositol-linked CP (GPI-CP) is the predominant form expressed in …
liver. Glycosylphosphatidylinositol-linked CP (GPI-CP) is the predominant form expressed in …
Cardiovascular involvement in patients affected by acromegaly: an appraisal
Cardiovascular complications are frequent in acromegalic patients. Several studies reported
increased prevalence of traditional cardiovascular risk factors and early development of …
increased prevalence of traditional cardiovascular risk factors and early development of …
Determinants of morbidities and mortality in acromegaly
L Kasuki, PS Rocha, EB Lamback… - … of endocrinology and …, 2019 - SciELO Brasil
Acromegaly is a systemic disease associated with increased morbidity, presenting
cardiovascular, metabolic, respiratory, neoplastic, endocrine, articular and bone …
cardiovascular, metabolic, respiratory, neoplastic, endocrine, articular and bone …
Acromegaly, inflammation and cardiovascular disease: a review
Acromegaly is characterized by Growth Hormone (GH) and Insulin-like Growth Factor 1 (IGF-
1) excess. Uncontrolled acromegaly is associated with a strongly increased risk of …
1) excess. Uncontrolled acromegaly is associated with a strongly increased risk of …
Overdosing on iron: Elevated iron and degenerative brain disorders
SR D'Mello, MC Kindy - Experimental Biology and Medicine, 2020 - journals.sagepub.com
All cells in organisms ranging from yeast to humans utilize iron as a cofactor or structural
element of proteins that function in diverse and critical cellular functions. However …
element of proteins that function in diverse and critical cellular functions. However …
The endothelium in acromegaly
P Maffei, F Dassie, A Wennberg, M Parolin… - Frontiers in …, 2019 - frontiersin.org
Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known
deleterious effects on the cardiovascular system, especially after long-term exposition …
deleterious effects on the cardiovascular system, especially after long-term exposition …
[HTML][HTML] Prepartum plane of energy intake affects serum biomarkers for inflammation and liver function during the periparturient period
Serum collected from multiparous Holsteins (n= 73) in a previous experiment was used to
determine the effect of prepartum plane of energy intake on metabolites related to …
determine the effect of prepartum plane of energy intake on metabolites related to …
Changes in metabolic parameters and cardiovascular risk factors after therapeutic control of acromegaly vary with the treatment modality. Data from the Bicêtre cohort …
Context Untreated acromegaly is associated with increased morbidity and mortality due to
malignant, cardiovascular, and cerebrovascular disorders. Effective treatment of acromegaly …
malignant, cardiovascular, and cerebrovascular disorders. Effective treatment of acromegaly …