Overview and limitations of database in global traditional medicines: A narrative review
X Li, J Zhang, X Shen, Y Zhang, D Guo - Acta Pharmacologica Sinica, 2024 - nature.com
The study of traditional medicine has garnered significant interest, resulting in various
research areas including chemical composition analysis, pharmacological research, clinical …
research areas including chemical composition analysis, pharmacological research, clinical …
Integration of Omics Data and Network Models to Unveil Negative Aspects of SARS-CoV-2, from Pathogenic Mechanisms to Drug Repurposing
L Bernardo, A Lomagno, PL Mauri, D Di Silvestre - Biology, 2023 - mdpi.com
Simple Summary SARS-CoV-2 caused the COVID-19 health emergency, affecting millions
of people worldwide. Samples collected from hospitalized or dead patients from the early …
of people worldwide. Samples collected from hospitalized or dead patients from the early …
CMAUP database update 2024: extended functional and association information of useful plants for biomedical research
Abstract Knowledge of the collective activities of individual plants together with the derived
clinical effects and targeted disease associations is useful for plant-based biomedical …
clinical effects and targeted disease associations is useful for plant-based biomedical …
[HTML][HTML] In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3
The organic anion transporters OAT1 (SLC22A6) and OAT3 (SLC22A8) are drug
transporters that are expressed in the kidney, with well-established roles in the in vivo …
transporters that are expressed in the kidney, with well-established roles in the in vivo …
COCONUT 2.0: a comprehensive overhaul and curation of the collection of open natural products database
V Chandrasekhar, K Rajan, SRS Kanakam… - Nucleic Acids …, 2024 - academic.oup.com
Abstract The COCONUT (COlleCtion of Open Natural prodUcTs) database was launched in
2021 as an aggregation of openly available natural product datasets and has been one of …
2021 as an aggregation of openly available natural product datasets and has been one of …
SIDERITE: Unveiling hidden siderophore diversity in the chemical space through digital exploration
Siderophore is a diverse family of secondary metabolites that exhibit high affinities for
binding and chelating iron, one of the essential elements for cellular processes, including …
binding and chelating iron, one of the essential elements for cellular processes, including …
Polymethoxylated flavonoids in citrus fruits: absorption, metabolism, and anticancer mechanisms against breast cancer
Y Wang, Y Mou, S Lu, Y Xia, B Cheng - PeerJ, 2024 - peerj.com
Polymethoxylated flavonoids (PMFs) are a subclass of flavonoids found in citrus fruits that
have shown multifunctional biological activities and potential anticancer effects against …
have shown multifunctional biological activities and potential anticancer effects against …
A comprehensive computational study to explore promising natural bioactive compounds targeting glycosyltransferase MurG in Escherichia coli for potential drug …
Peptidoglycan is a carbohydrate with a cross-linked structure that protects the cytoplasmic
membrane of bacterial cells from damage. The mechanism of peptidoglycan biosynthesis …
membrane of bacterial cells from damage. The mechanism of peptidoglycan biosynthesis …
[HTML][HTML] Natural Product Databases for Drug Discovery: Features and Applications
Natural products (NPs) exhibit diverse chemical structures and biological activities that make
them valuable sources for drug discovery. With advancements in computational technology …
them valuable sources for drug discovery. With advancements in computational technology …
Natural Products Dereplication: Databases and Analytical Methods
I Pérez-Victoria - Progress in the Chemistry of Organic Natural Products …, 2024 - Springer
The development of efficient methods for dereplication has been critical in the re-emergence
of the research in natural products as a source of drug leads. Current dereplication …
of the research in natural products as a source of drug leads. Current dereplication …