Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Vascular remodelling in cardiovascular diseases: hypertension, oxidation, and inflammation

J Totoń-Żurańska, TP Mikolajczyk, B Saju… - Clinical …, 2024 - portlandpress.com
Optimal vascular structure and function are essential for maintaining the physiological
functions of the cardiovascular system. Vascular remodelling involves changes in vessel …

Oxidative stress: roles in skeletal muscle atrophy

H Zhang, G Qi, K Wang, J Yang, Y Shen, X Yang… - Biochemical …, 2023 - Elsevier
Oxidative stress, inflammation, mitochondrial dysfunction, reduced protein synthesis, and
increased proteolysis are all critical factors in the process of muscle atrophy. In particular …

Phytochemicals and biological activities of walnut septum: A systematic review

L Mateș, ME Rusu, DS Popa - Antioxidants, 2023 - mdpi.com
In the last few decades, scientific evidence has stressed the importance of plants in the
prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age …

Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptations

KE Pendleton, K Wang, GV Echeverria - Frontiers in Cell and …, 2023 - frontiersin.org
Deregulation of tumor cell metabolism is widely recognized as a “hallmark of cancer.” Many
of the selective pressures encountered by tumor cells, such as exposure to anticancer …

Catalyzing innovation: Exploring iron oxide nanoparticles-Origins, advancements, and future application horizons

P Kumar, N Thakur, K Kumar, S Kumar, A Dutt… - Coordination Chemistry …, 2024 - Elsevier
Iron oxides, including wustite (FeO), hematite (α-Fe 2 O 3), maghemite (γ-Fe 2 O 3), and
magnetite (Fe 3 O 4), are remarkable nanomaterials. Iron oxide nanoparticles (IONPs) at the …

Reactive oxidant species induced by antifungal drugs: identity, origins, functions, and connection to stress-induced cell death

I Gonzalez-Jimenez, DS Perlin, E Shor - Frontiers in Cellular and …, 2023 - frontiersin.org
Reactive oxidant species (ROS) are unstable, highly reactive molecules that are produced
by cells either as byproducts of metabolism or synthesized by specialized enzymes. ROS …

New insights into oxidative stress and inflammatory response in neurodegenerative diseases

E Scarian, C Viola, F Dragoni, R Di Gerlando… - International Journal of …, 2024 - mdpi.com
Oxidative stress (OS) and inflammation are two important and well-studied pathological
hallmarks of neurodegenerative diseases (NDDs). Due to elevated oxygen consumption, the …

Mitochondrial dysfunction in cardiac diseases and therapeutic strategies

Y Huang, B Zhou - Biomedicines, 2023 - mdpi.com
Mitochondria are the main site of intracellular synthesis of ATP, which provides energy for
various physiological activities of the cell. Cardiomyocytes have a high density of …

Oxidative stress and the Nrf2/PPARγ Axis in the endometrium: insights into female fertility

P Artimovič, Z Badovská, S Toporcerová, I Špaková… - Cells, 2024 - mdpi.com
Successful pregnancy depends on precise molecular regulation of uterine physiology,
especially during the menstrual cycle. Deregulated oxidative stress (OS), often influenced by …