Annexin A1 as a regulator of immune response in cancer
TG Araújo, STS Mota, HSV Ferreira, MA Ribeiro… - Cells, 2021 - mdpi.com
Annexin A1 is a 37 kDa phospholipid-binding protein that is expressed in many tissues and
cell types, including leukocytes, lymphocytes and epithelial cells. Although Annexin A1 has …
cell types, including leukocytes, lymphocytes and epithelial cells. Although Annexin A1 has …
Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria
C Dahlgren, M Gabl, A Holdfeldt, M Winther… - Biochemical …, 2016 - Elsevier
Proper recruitment and activation of neutrophils to/at sites of infection/inflammation relies
largely on the surface expression of chemoattractant receptors of which a formyl peptide …
largely on the surface expression of chemoattractant receptors of which a formyl peptide …
Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria
Inborn errors of human interferon gamma (IFN-γ) immunity underlie mycobacterial disease.
We report a patient with mycobacterial disease due to inherited deficiency of the …
We report a patient with mycobacterial disease due to inherited deficiency of the …
The viral protein corona directs viral pathogenesis and amyloid aggregation
Artificial nanoparticles accumulate a protein corona layer in biological fluids, which
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …
The meningeal transcriptional response to traumatic brain injury and aging
Emerging evidence suggests that the meningeal compartment plays instrumental roles in
various neurological disorders, however, we still lack fundamental knowledge about …
various neurological disorders, however, we still lack fundamental knowledge about …
The attenuation of diabetic nephropathy by annexin A1 via regulation of lipid metabolism through the AMPK/PPARα/CPT1b pathway
L Wu, C Liu, DY Chang, R Zhan, M Zhao… - Diabetes, 2021 - Am Diabetes Assoc
Inflammation and abnormal metabolism play important roles in the pathogenesis of diabetic
nephropathy (DN). Annexin A1 (ANXA1) contributes to inflammation resolution and …
nephropathy (DN). Annexin A1 (ANXA1) contributes to inflammation resolution and …
Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics
V Gerke, FNE Gavins, M Geisow, T Grewal… - Nature …, 2024 - nature.com
Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic
phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+ …
phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+ …
Annexin A1 localization and its relevance to cancer
Z Boudhraa, B Bouchon, C Viallard, M D'Incan… - Clinical …, 2016 - portlandpress.com
Annexin A1 (ANXA1) is a Ca2+-regulated phospholipid-binding protein involved in various
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …
Dysregulation of TFH-BTRM lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer
Patients with non-small cell lung cancer (NSCLC) with epidermal growth factor receptor
(EGFR) mutations exhibit an unfavorable response to PD-1 inhibitor through unclear …
(EGFR) mutations exhibit an unfavorable response to PD-1 inhibitor through unclear …
An overview on immunogenic cell death in cancer biology and therapy
MC Rodrigues, JAV Morais, R Ganassin, GRT Oliveira… - Pharmaceutics, 2022 - mdpi.com
Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to
promote an adaptive immune response against antigens of the dying cell in an …
promote an adaptive immune response against antigens of the dying cell in an …