Tissue engineering (TE) is a strongly expanding research area. TE approaches require
biocompatible scaffolds, cells, and different applied stimuli, which altogether mimic the …

Tendon disease is a significant and growing burden to healthcare systems. One strategy to
address this challenge is tissue engineering. A widely held view in this field is that …

Tendon injury is the most common disease in the musculoskeletal system. The current
treatment methods have many limitations, such as poor therapeutic effects, functional loss of …

A range of bioreactors use linear actuators to apply tensile forces in vitro, but differences in
their culture environments can limit a direct comparison between studies. The widespread …

Studying the crosstalk between the muscle and tendon tissue is an important yet
understudied area in musculoskeletal research. In vitro models can help elucidate the …

Cell-based tendon therapies with tenocytes as a cell source need effective tenocyte in vitro
expansion before application for tendinopathies and tendon injuries. Supplementation of …

Tissue-engineered decellularized matrices can progress clinical replacement of full-
thickness ruptures or tendon defects. This study develops and validates a custom-made …

Tear on the tendon, ligament and articular cartilage of the joints do not heal by itself and new
modalities of treatment are required to address the need for full restoration of joint functions …

The myotendinous junction (MTJ) is the interface connecting skeletal muscle and tendon
tissues. This specialized region represents the bridge that facilitates the transmission of …

A key objective of tissue engineering (TE) is to produce in vitro funcional grafts that can
replace damaged tissues or organs in patients. TE uses bioreactors, which are controlled …