Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

Serum protein as naturally essential biomacromolecules has recently emerged as a
versatile carrier for diagnostic and therapeutic drug delivery for cancer nanomedicine with …

Allosteric modulation of protein function, wherein the binding of an effector to a protein
triggers conformational changes at distant functional sites, plays a central part in the control …

Simple Summary Recently, several studies have shown that acidosis, which is increased
acidity in the blood and other body tissues, is often associated with severe COVID-19. In this …

Nanoparticles (NPs) are increasingly used in a wide variety of applications and products;
however, NPs may affect stress response pathways and interact with proteins in biological …

Carbon monoxide (CO) has been firmly established as an endogenous signaling molecule
with a variety of pathophysiological and pharmacological functions, including …

Iron single‐atom nanozymes represent a promising artificial enzyme with superior activity
owing to uniform active sites that can precisely mimic active center of nature enzymes …

The production of erythropoietin (EPO), the main regulator of erythroid differentiation, is
regulated by hypoxia-inducible factor (HIF). HIF2α seems to be the principal regulator of …

Blood storage promotes the rapid depletion of red blood cell (RBC) high-energy adenosine
triphosphate (ATP) and 2, 3-diphosphoglycerate (DPG), which are critical regulators of …

The fabrication of functional assemblies with defined structures through controllable
molecular packing under physiological conditions is challenging. Here, modularly designed …