Myeloid-derived suppressor cells (MDSC) are generated during tumor progression and
suppress the anti-tumor functions of T and natural killer (NK) cells. Their enrichment is …

More than 250 million people are living with chronic hepatitis B despite the availability of
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …

Metastatic cancer accounts for 90% of all cancer-related deaths and continues to be one of
the toughest challenges in cancer treatment. A growing body of data indicates that S100A9 …

Myeloid derived suppressor cells (MDSC) are heterogeneous populations that through the
release of soluble factors and/or by cell-to-cell interactions suppress both innate and …

Bone marrow (BM) is a highly complex tissue that provides important regulatory signals to
orchestrate hematopoiesis. Resident and transient cells occupy and interact with some well …

Dendritic cells (DCs), a class of professional antigen-presenting cells, are considered key
factors in the initiation and maintenance of anti-tumor immunity due to their powerful ability …

Myeloid-derived suppressor cells (MDSCs) are immune cells of the myeloid lineage that
progressively accumulate in tumors and play an important role in promoting tumor growth …

FAT atypical cadherin 1 (FAT1) promotes glioblastoma (GBM) by promoting protumorigenic
inflammatory cytokine expression in tumor cells. However, tumors also have an …

Tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs)
play a critical role in resistance to immunotherapy. In this study, we identified epidermal …

The expansion of myeloid-derived suppressor cells (MDSCs), known as heterogeneous
population of immature myeloid cells, is enhanced during several pathological conditions …