[HTML][HTML] Automating the design-build-test-learn cycle towards next-generation bacterial cell factories

N Gurdo, DC Volke, D McCloskey, PI Nikel - New Biotechnology, 2023 - Elsevier
Automation is playing an increasingly significant role in synthetic biology. Groundbreaking
technologies, developed over the past 20 years, have enormously accelerated the …

Bacterial strain typing in the genomic era

W Li, D Raoult, PE Fournier - FEMS microbiology reviews, 2009 - academic.oup.com
Bacterial strain typing, or identifying bacteria at the strain level, is particularly important for
diagnosis, treatment, and epidemiological surveillance of bacterial infections. This is …

Real-time kinetics of gene activity in individual bacteria

I Golding, J Paulsson, SM Zawilski, EC Cox - Cell, 2005 - cell.com
Protein levels have been shown to vary substantially between individual cells in clonal
populations. In prokaryotes, the contribution to such fluctuations from the inherent …

Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays

JA Bernstein, AB Khodursky, PH Lin… - Proceedings of the …, 2002 - National Acad Sciences
Much of the information available about factors that affect mRNA decay in Escherichia coli,
and by inference in other bacteria, has been gleaned from study of less than 25 of the≈ …

EcoCyc: a comprehensive database of Escherichia coli biology

IM Keseler, J Collado-Vides… - Nucleic acids …, 2010 - academic.oup.com
Abstract EcoCyc (http://EcoCyc. org) is a comprehensive model organism database for
Escherichia coli K-12 MG1655. From the scientific literature, EcoCyc captures the functions …

DNA Microarray-Mediated Transcriptional Profiling of the Escherichia coli Response to Hydrogen Peroxide

M Zheng, X Wang, LJ Templeton… - Journal of …, 2001 - Am Soc Microbiol
The genome-wide transcription profile of Escherichia coli cells treated with hydrogen
peroxide was examined with a DNA microarray composed of 4,169 E. coli open reading …

Biodegradation of aromatic compounds: current status and opportunities for biomolecular approaches

B Cao, K Nagarajan, KC Loh - Applied microbiology and biotechnology, 2009 - Springer
Biodegradation can achieve complete and cost-effective elimination of aromatic pollutants
through harnessing diverse microbial metabolic processes. Aromatics biodegradation plays …

Overflow Metabolism in Escherichia coli during Steady-State Growth: Transcriptional Regulation and Effect of the Redox Ratio

GN Vemuri, E Altman, DP Sangurdekar… - Applied and …, 2006 - Am Soc Microbiol
Overflow metabolism in the form of aerobic acetate excretion by Escherichia coli is an
important physiological characteristic of this common industrial microorganism. Although …

Nitrogen regulatory protein C-controlled genes of Escherichia coli: Scavenging as a defense against nitrogen limitation

DP Zimmer, E Soupene, HL Lee… - Proceedings of the …, 2000 - National Acad Sciences
Nitrogen regulatory protein C (NtrC) of enteric bacteria activates transcription of
genes/operons whose products minimize the slowing of growth under nitrogen-limiting …

Tapping into microbial diversity

M Keller, K Zengler - Nature Reviews Microbiology, 2004 - nature.com
Even though significant advances have been made in understanding microbial diversity,
most microorganisms are still only characterized by'molecular fingerprints' and have resisted …