Myeloid malignancies are devastating hematologic cancers with limited therapeutic options.
Inflammation is emerging as a novel driver of myeloid malignancy, with important …

Introduction Mast cells are found in all tissues and express numerous surface receptors
allowing them to sense and respond to allergic, autoimmune, environmental …

Mast cells have existed for millions of years in species that never suffer from allergic
reactions. Hence, in addition to allergies, mast cells can play a critical role in homeostasis …

Increasingly, patients with gastrointestinal tumors can benefit from immunotherapy, but not
patients with pancreatic cancer. While this lack of benefit has been attributed to lower T-cell …