Brain-derived neurotrophic factor and neuropsychiatric disorders

AE Autry, LM Monteggia - Pharmacological reviews, 2012 - ASPET
Brain derived neurotrophic factor (BDNF) is the most prevalent growth factor in the central
nervous system (CNS). It is essential for the development of the CNS and for neuronal …

Genetics and epigenetics of eating disorders

Z Yilmaz, JA Hardaway, CM Bulik - Advances in genomics and …, 2015 - Taylor & Francis
Eating disorders (EDs) are serious psychiatric conditions influenced by biological,
psychological, and sociocultural factors. A better understanding of the genetics of these …

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

M Notaras, R Hill, M van den Buuse - Molecular psychiatry, 2015 - nature.com
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …

The genetics of eating disorders

SE Trace, JH Baker, E Peñas-Lledó… - Annual review of …, 2013 - annualreviews.org
Over the past decade, considerable advances have been made in understanding genetic
influences on eating pathology. Eating disorders aggregate in families, and twin studies …

The lighter side of BDNF

EE Noble, CJ Billington, CM Kotz… - American Journal of …, 2011 - journals.physiology.org
Brain-derived neurotrophic factor (BDNF) mediates energy metabolism and feeding
behavior. As a neurotrophin, BDNF promotes neuronal differentiation, survival during early …

Obesity: genes, brain, gut, and environment

UN Das - Nutrition, 2010 - Elsevier
Obesity, which is assuming alarming proportions, has been attributed to genetic factors,
hypothalamic dysfunction, and intestinal gut bacteria and an increase in the consumption of …

[HTML][HTML] The role of ghrelin in anorexia nervosa

MA Schalla, A Stengel - International journal of molecular sciences, 2018 - mdpi.com
Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the
stomach, is the only known peripherally produced and centrally acting peptide that …

[HTML][HTML] A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?

SJ Brooks, M Rask-Andersen, C Benedict, HB Schiöth - BMC psychiatry, 2012 - Springer
Background Sixty percent of eating disorders do not meet criteria for anorexia-or bulimia
nervosa, as defined by the Diagnostic and Statistical Manual version 4 (DSM-IV). Instead …

AgRP neurons coordinate the mitigation of activity-based anorexia

AK Sutton Hickey, SC Duane, LE Mickelsen… - Molecular …, 2023 - nature.com
Anorexia nervosa (AN) is a debilitating and deadly disease characterized by low body mass
index due to diminished food intake, and oftentimes concurrent hyperactivity. A high …

Ghrelin in psychiatric disorders–a review

DA Wittekind, M Kluge - Psychoneuroendocrinology, 2015 - Elsevier
Ghrelin is a 28-amino-acid peptide hormone, first described in 1999 and broadly expressed
in the organism. As the only known orexigenic hormone secreted in the periphery, it …