The dynamic lung microbiome in health and disease
JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …
light into the microbial world of the respiratory tract. Long considered to be a sterile …
The gut-lung axis in health and respiratory diseases: a place for inter-organ and inter-kingdom crosstalks
R Enaud, R Prevel, E Ciarlo, F Beaufils… - Frontiers in cellular …, 2020 - frontiersin.org
The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …
complex pathways involving their respective microbiota have reinforced the existence of a …
The lung microbiome: progress and promise
SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …
Role of probiotics to combat viral infections with emphasis on COVID-19
Interspecies transmissions of viruses between animals and humans may result in
unpredictable pathogenic potential and new transmissible diseases. This mechanism has …
unpredictable pathogenic potential and new transmissible diseases. This mechanism has …
Emerging pathogenic links between microbiota and the gut–lung axis
The microbiota is vital for the development of the immune system and homeostasis.
Changes in microbial composition and function, termed dysbiosis, in the respiratory tract and …
Changes in microbial composition and function, termed dysbiosis, in the respiratory tract and …
Lung microbiome: new insights into the pathogenesis of respiratory diseases
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
Inflammatory endotype–associated airway microbiome in chronic obstructive pulmonary disease clinical stability and exacerbations: a multicohort longitudinal …
Z Wang, N Locantore, K Haldar… - American journal of …, 2021 - atsjournals.org
Rationale: Understanding the role of the airway microbiome in chronic obstructive
pulmonary disease (COPD) inflammatory endotypes may help to develop microbiome …
pulmonary disease (COPD) inflammatory endotypes may help to develop microbiome …
The microbiome and the respiratory tract
RP Dickson, JR Erb-Downward… - Annual review of …, 2016 - annualreviews.org
Although the notion that “the normal lung is free from bacteria” remains common in
textbooks, it is virtually always stated without citation or argument. The lungs are constantly …
textbooks, it is virtually always stated without citation or argument. The lungs are constantly …
Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype
LN Segal, JC Clemente, JCJ Tsay, SB Koralov… - Nature …, 2016 - nature.com
Microaspiration is a common phenomenon in healthy subjects, but its frequency is increased
in chronic inflammatory airway diseases, and its role in inflammatory and immune …
in chronic inflammatory airway diseases, and its role in inflammatory and immune …
The gut–lung axis in respiratory disease
BJ Marsland, A Trompette… - Annals of the American …, 2015 - atsjournals.org
Host–microorganism interactions shape local cell functionality, immune responses, and can
influence disease development. Evidence indicates that the impact of host–microbe …
influence disease development. Evidence indicates that the impact of host–microbe …