Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …

In the nervous system, the intracellular chloride concentration ([Cl−] i) determines the
strength and polarity of γ-aminobutyric acid (GABA)-mediated neurotransmission.[Cl−] i is …

Seizures are the most common neurological emergency in the neonatal period and in
contrast to those in infancy and childhood, are often provoked seizures with an acute cause …

Background Despite the availability of continuous conventional electroencephalography
(cEEG), accurate diagnosis of neonatal seizures is challenging in clinical practice …

This article offers the preferred methods and indications for longterm, conventional
electroencephalography (EEG) monitoring for selected, high-risk neonates of postmenstrual …

During development, activation of Cl−-permeable GABAA receptors (GABAA-R) excites
neurons as a result of elevated intracellular Cl− levels and a depolarized Cl− equilibrium …

Background: Neonatal seizures are often subclinical, making accurate diagnosis difficult.
Objective: To describe the clinical manifestations of electrographic seizures recorded on …

Neonatal seizures occur in their majority in close temporal relation to an acute brain injury or
systemic insult, and are accordingly defined as acute symptomatic or provoked seizures …

Background Infantile spasms (West's Syndrome) is a syndrome that includes a peculiar type
of epileptic seizure—the spasms—and an electroencephalographic (EEG) abnormality often …

In childhood, the risk for seizures is greatest in the neonatal period. Currently used therapies
have limited efficacy. Although the treatment of neonatal seizures has not significantly …