Oxidative stress emerges as a critical mechanism underlying the development and
progression of various brain diseases, arising from either increased generation of reactive …

Neuroethical questions raised by recent advances in the diagnosis and treatment of
disorders of consciousness are rapidly expanding, increasingly relevant and yet …

Background Recovery trajectories of clinically unresponsive patients with acute brain injury
are largely uncertain. Brain activation in the absence of a behavioural response to spoken …

Accurate outcome detection in neuro-rehabilitative settings is crucial for appropriate long-
term rehabilitative decisions in patients with disorders of consciousness (DoC). EEG …

Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

Early reemergence of consciousness predicts long-term functional recovery for patients with
severe brain injury. However, tools to reliably detect consciousness in the intensive care unit …

Abstract Functional MRI (fMRI) and EEG may reveal residual consciousness in patients with
disorders of consciousness (DoC), as reflected by a rapidly expanding literature on chronic …

The default mode network (DMN) mediates self-awareness and introspection, core
components of human consciousness. Therapies to restore consciousness in patients with …

Each neuroimaging technique conveys advantages and pitfalls to assess consciousness.
We recommend a multimodal approach in which complementary techniques provide …

Neuroprognostication, or the prediction of recovery from disorders of consciousness caused
by severe brain injury, is as critical as it is complex. With profound implications for mortality …