[HTML][HTML] The immune privilege of the intervertebral disc: implications for intervertebral disc degeneration treatment
Z Sun, B Liu, ZJ Luo - International journal of medical sciences, 2020 - ncbi.nlm.nih.gov
The intervertebral disc (IVD) is the largest avascular organ of the body. It is composed of
three parts: the nucleus pulposus (NP), the annulus fibrosus (AF) and the cartilaginous …
three parts: the nucleus pulposus (NP), the annulus fibrosus (AF) and the cartilaginous …
Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function
S Chen, P Fu, H Wu, M Pei - Cell and tissue research, 2017 - Springer
The degradation of cartilage in the human body is impacted by aging, disease, genetic
predisposition and continued insults resulting from daily activity. The burden of cartilage …
predisposition and continued insults resulting from daily activity. The burden of cartilage …
Ageing in the musculoskeletal system: Cellular function and dysfunction throughout life
S Roberts, P Colombier, A Sowman, C Mennan… - Acta …, 2016 - Taylor & Francis
The extent of ageing in the musculoskeletal system during the life course affects the quality
and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed …
and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed …
Accumulation and localization of macrophage phenotypes with human intervertebral disc degeneration
KR Nakazawa, BA Walter, DM Laudier… - The Spine Journal, 2018 - Elsevier
Abstract Background Context Chronic inflammation is an important component of
intervertebral disc (IVD) degeneration, but there is limited knowledge about the identity and …
intervertebral disc (IVD) degeneration, but there is limited knowledge about the identity and …
[HTML][HTML] Progress in regulating inflammatory biomaterials for intervertebral disc regeneration
H Xiang, W Zhao, K Jiang, J He, L Chen, W Cui, Y Li - Bioactive Materials, 2024 - Elsevier
Intervertebral disc degeneration (IVDD) is rising worldwide and leading to significant health
issues and financial strain for patients. Traditional treatments for IVDD can alleviate pain but …
issues and financial strain for patients. Traditional treatments for IVDD can alleviate pain but …
Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities
Background Intervertebral disc degeneration has an annual worldwide socioeconomic
impact masked as low back pain of over 70 billion euros. This disease has a high …
impact masked as low back pain of over 70 billion euros. This disease has a high …
[HTML][HTML] Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs
ML Terpstra, J Li, A Mensinga, M de Ruijter… - …, 2022 - iopscience.iop.org
Microvasculature is essential for the exchange of gas and nutrient for most tissues in our
body. Some tissue structures such as the meniscus presents spatially confined blood …
body. Some tissue structures such as the meniscus presents spatially confined blood …
Vascularization of the human intervertebral disc: a scoping review
Intervertebral discs (IVDs) are often referred to as the largest avascular structures of the
human body, yet a collective resource characterizing the vascularization of the IVD does not …
human body, yet a collective resource characterizing the vascularization of the IVD does not …
[HTML][HTML] The potential role of melatonin in retarding intervertebral disc ageing and degeneration: a systematic review
Z Cheng, Q Xiang, J Wang, Y Zhang - Ageing Research Reviews, 2021 - Elsevier
Intervertebral disc degeneration (IDD) is a common degenerative disease of the
musculoskeletal system that develops with age. It is regarded as the main cause of chronic …
musculoskeletal system that develops with age. It is regarded as the main cause of chronic …
Notochordal cell-based treatment strategies and their potential in intervertebral disc regeneration
FC Bach, DW Poramba-Liyanage… - Frontiers in Cell and …, 2022 - frontiersin.org
Chronic low back pain is the number one cause of years lived with disability. In about 40% of
patients, chronic lower back pain is related to intervertebral disc (IVD) degeneration. The …
patients, chronic lower back pain is related to intervertebral disc (IVD) degeneration. The …