In the last few decades, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding perpetually …

Berberine, an isoquinoline alkaloid of the protoberberine type found in an array of plants,
has been used in Indian and Chinese medicines as an antimicrobial, stomachic, bitter tonic …

In the past decade, the potential of harnessing the ability of nuclear magnetic resonance
(NMR) spectroscopy to monitor intermolecular interactions as a tool for drug discovery has …

In recent years considerable effort has been devoted to increasing the success rate of the
drug discovery process [1–7]. The focus has been mainly on quantity and speed …

Twenty-one known Amaryllidaceae alkaloids of various structural types and one
undescribed alkaloid, named narcimatuline, have been isolated from fresh bulbs of …

Although fluorine plays only a minor role in biology, its physicochemical properties have
proven incredibly useful in the design of analogues of biologically important molecules …

Berberine, a natural isoquinoline alkaloid, is used in herbal medicine and has recently been
shown to have efficacy in the treatment of mood disorders. Furthermore, berberine …

Three new alkaloids, bersavine (3), muraricine (4), and berbostrejdine (8), together with
seven known isoquinoline alkaloids (1–2, 5–7, 9, and 10) were isolated from an alkaloidal …

This study aims to determine the potential antioxidant, antihypertensive, hypoglycaemic and
nootropic activity of a purified polyphenolic extract from the halophyte ice plant …

Significant number of studies has been performed to find alternatives or treatments for
diseases of the nervous forum by identifying structures with activity at the central nervous …