Inflammatory bowel disease (IBD), comprised of Crohn's disease (CD) and ulcerative colitis
(UC), is a group of chronic inflammatory disorders. IBD is regarded as a severe healthcare …

With rising global temperatures, heat-related mortality is increasing, particularly among older
adults. Although this is often attributed to declines in thermoregulatory function, little is …

Autophagy is a vital cellular process, essential to maintaining cellular function during acute
physiological stressors including exercise and heat stress. We previously showed that …

Autophagy is essential to maintaining cellular homeostasis in all eukaryotic cells and to
tolerance of acute stressors such as starvation, heat, and recovery after exercise. Limited …

Hypothermia is a critical consequence of extreme cold exposure that increases the risk of
cold-related injury and death in humans. While the initiation of cytoprotective mechanisms …

Heat waves can cause dangerous elevations in body temperature that can compromise
cellular function and increase the risk of heat stroke and major cardiovascular events …

To protect vulnerable populations during heat waves, public health agencies recommend
maintaining indoor air temperature below∼ 24–28° C. While we recently demonstrated that …

Temperature is a crucial environmental factor that affects embryonic development,
particularly for marine organisms with long embryonic development periods. However, the …

Autophagy is a crucial cytoprotective mechanism preventing the accumulation of cellular
damage, especially during external stimuli such as cold exposure. Older adults poorly …

Heat-stress-induced dehydration is associated with extracellular hyperosmolality. To
counteract the associated stress, cells employ cytoprotective mechanisms, including …