Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics
S Ardui, A Ameur, JR Vermeesch… - Nucleic acids …, 2018 - academic.oup.com
Short read massive parallel sequencing has emerged as a standard diagnostic tool in the
medical setting. However, short read technologies have inherent limitations such as GC …
medical setting. However, short read technologies have inherent limitations such as GC …
Review of clinical next-generation sequencing
S Yohe, B Thyagarajan - Archives of pathology & …, 2017 - meridian.allenpress.com
Context.—Next-generation sequencing (NGS) is a technology being used by many
laboratories to test for inherited disorders and tumor mutations. This technology is new for …
laboratories to test for inherited disorders and tumor mutations. This technology is new for …
[HTML][HTML] One chromosome, one contig: complete microbial genomes from long-read sequencing and assembly
S Koren, AM Phillippy - Current opinion in microbiology, 2015 - Elsevier
Highlights•We describe three long-read sequencing technologies and their
characteristics.•We describe available algorithms for long-read assembly and their …
characteristics.•We describe available algorithms for long-read assembly and their …
The present and future of de novo whole-genome assembly
As the advent of next-generation sequencing (NGS) technology, various de novo assembly
algorithms based on the de Bruijn graph have been developed to construct chromosome …
algorithms based on the de Bruijn graph have been developed to construct chromosome …
Whole genome sequencing in clinical and public health microbiology
Genomics and whole genome sequencing (WGS) have the capacity to greatly enhance
knowledge and understanding of infectious diseases and clinical microbiology. The growth …
knowledge and understanding of infectious diseases and clinical microbiology. The growth …
Next-generation sequencing (NGS) in the microbiological world: How to make the most of your money
The Sanger sequencing method produces relatively long DNA sequences of unmatched
quality and has been considered for long time as the gold standard for sequencing DNA …
quality and has been considered for long time as the gold standard for sequencing DNA …
FMLRC: Hybrid long read error correction using an FM-index
Background Long read sequencing is changing the landscape of genomic research,
especially de novo assembly. Despite the high error rate inherent to long read technologies …
especially de novo assembly. Despite the high error rate inherent to long read technologies …
Vegetation biomass and soil moisture coregulate bacterial community succession under altered precipitation regimes in a desert steppe in northwestern China
X Na, H Yu, P Wang, W Zhu, Y Niu, J Huang - Soil Biology and …, 2019 - Elsevier
Given that soil water availability is the major limitation on plant growth in desert steppes,
uncovering the connections between belowground and aboveground communities under …
uncovering the connections between belowground and aboveground communities under …
Complete chloroplast genome of Lilium ledebourii (Baker) Boiss and its comparative analysis: lights into selective pressure and adaptive evolution
Abstract Lilium ledebourii (Baker) Boiss is a rare species, which exhibits valuable traits.
However, before its genetic diversity and evolutionary were uncovered, its wild resources …
However, before its genetic diversity and evolutionary were uncovered, its wild resources …
Primer ID validates template sampling depth and greatly reduces the error rate of next-generation sequencing of HIV-1 genomic RNA populations
Validating the sampling depth and reducing sequencing errors are critical for studies of viral
populations using next-generation sequencing (NGS). We previously described the use of …
populations using next-generation sequencing (NGS). We previously described the use of …