The role of reward circuitry and food addiction in the obesity epidemic: An update

SJ Leigh, MJ Morris - Biological psychology, 2018 - Elsevier
The increasing worldwide prevalence of obesity is partially related to the ready availability of
highly palatable foods which increases the incidence of hedonic, non-homeostatic feeding …

Cocaine-and amphetamine-regulated transcript (CART): a multifaceted neuropeptide

H Ahmadian-Moghadam, MS Sadat-Shirazi… - Peptides, 2018 - Elsevier
Over the last 35 years, the continuous discovery of novel neuropeptides has been the key to
the better understanding of how the central nervous system has integrated with neuronal …

Early life stress and the programming of eating behavior and anxiety: Sex-specific relationships with serotonergic activity and hypothalamic neuropeptides

RMS de Lima, LV dos Santos Bento… - Behavioural brain …, 2020 - Elsevier
Early life experiences have strong influences on brain programming and can affect eating
behavior control and body weight later in life. However, there is no consensus about the …

Removal of high-fat diet after chronic exposure drives binge behavior and dopaminergic dysregulation in female mice

JL Carlin, SE McKee, T Hill-Smith, NM Grissom… - Neuroscience, 2016 - Elsevier
A significant contributor to the obesity epidemic is the overconsumption of highly palatable,
energy dense foods. Chronic intake of palatable foods is associated with neuroadaptations …

[HTML][HTML] Bisphenol A causes liver damage and selectively alters the neurochemical coding of intrahepatic parasympathetic nerves in juvenile porcine models under …

M Thoene, L Rytel, E Dzika, A Włodarczyk… - International journal of …, 2017 - mdpi.com
Bisphenol A (BPA) is an extremely common polymer that is used in typical everyday
products throughout the world, especially in food and beverage containers. Within the last …

Demystifying functional role of cocaine-and amphetamine-related transcript (CART) peptide in control of energy homeostasis: A twenty-five year expedition

A Singh, AM de Araujo, JP Krieger, M Vergara, CK Ip… - Peptides, 2021 - Elsevier
Cocaine-and amphetamine-related transcript (CART) is a neuropeptide first discovered in
the striatum of the rat brain. Later, the genetic sequence and function of CART peptide …

Investigating a role of orexin and 'cocaine-and amphetamine-regulated transcript'in the nucleus accumbens shell in binge eating of male rats and the relationship with …

J Schuller, M Koch - Physiology & Behavior, 2022 - Elsevier
Binge eating disorder (BED) is the most prevalent eating disorder in the adult population. It
is characterized by recurrent episodes of uncontrollable overconsumption of palatable food …

CART neurons in the lateral hypothalamus communicate with the nucleus accumbens shell via glutamatergic neurons in paraventricular thalamic nucleus to modulate …

AG Choudhary, AR Somalwar, S Sagarkar… - Brain Structure and …, 2018 - Springer
Paraventricular thalamic nucleus (PVT) serves as a transit node processing food and drug-
associated reward information, but its afferents and efferents have not been fully defined. We …

Diversity in the lateral hypothalamic input to the ventral tegmental area

N Godfrey, SL Borgland - Neuropharmacology, 2019 - Elsevier
The obesity epidemic is one of the biggest health challenges globally and rates have tripled
since 1975. Overeating is the largest determinant of obesity, yet little is understood of the …

Pro‐cognitive action of CART is mediated via ERK in the hippocampus

AP Bharne, CD Borkar, S Bodakuntla, M Lahiri… - …, 2016 - Wiley Online Library
Although cocaine‐and amphetamine‐regulated transcript peptide (CART) is detected in
several cortical and subcortical areas, its role in higher functions has been largely ignored …